Late reaction to ustekinumab infusion
Psoriasis is a chronic inflammatory disease that directly affects the quality of life. Biologics are prescribed for patients unresponsive to conventional treatments and with severe forms of the disease. Ustekinumab is a fully human monoclonal antibody against the p40 subunit of interleukins 12/23 th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2013-09-01
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| Series: | Dermatology Reports |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/dr/article/view/4976 |
| _version_ | 1818305922759393280 |
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| author | Marina Resener Morais Luana Pizarro Meneghello Carina Flores de Oliveira André Vicente Esteves Carvalho |
| author_facet | Marina Resener Morais Luana Pizarro Meneghello Carina Flores de Oliveira André Vicente Esteves Carvalho |
| author_sort | Marina Resener Morais |
| collection | DOAJ |
| description | Psoriasis is a chronic inflammatory disease that directly affects the quality of life. Biologics are prescribed for patients unresponsive to conventional treatments and with severe forms of the disease. Ustekinumab is a fully human monoclonal antibody against the p40 subunit of interleukins 12/23 that is being used with satisfactory responses, achieving an improvement in the baseline Psoriasis Area and Severity Index of approximately 75% after 12 weeks of treatment. It has few side effects, including grater susceptibility to infections and development of reactions to the drug. Our report discusses a case of a cutaneous reaction to the use of ustekinumab in a 27 year-old male patient after the third dose of the medication. No similar case has been reported in the literature. |
| first_indexed | 2024-12-13T06:34:17Z |
| format | Article |
| id | doaj.art-369c2ecd89d2474980891131aafdb2d8 |
| institution | Directory Open Access Journal |
| issn | 2036-7392 2036-7406 |
| language | English |
| last_indexed | 2024-12-13T06:34:17Z |
| publishDate | 2013-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj.art-369c2ecd89d2474980891131aafdb2d82022-12-21T23:56:33ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062013-09-0151e2e210.4081/dr.2013.e22598Late reaction to ustekinumab infusionMarina Resener Morais0Luana Pizarro Meneghello1Carina Flores de Oliveira2André Vicente Esteves Carvalho3Irmandade Santa Casa de Misericórdia de Porto AlegreIrmandade Santa Casa de Misericórdia de Porto AlegreIrmandade Santa Casa de Misericórdia de Porto AlegreIrmandade Santa Casa de Misericórdia de Porto AlegrePsoriasis is a chronic inflammatory disease that directly affects the quality of life. Biologics are prescribed for patients unresponsive to conventional treatments and with severe forms of the disease. Ustekinumab is a fully human monoclonal antibody against the p40 subunit of interleukins 12/23 that is being used with satisfactory responses, achieving an improvement in the baseline Psoriasis Area and Severity Index of approximately 75% after 12 weeks of treatment. It has few side effects, including grater susceptibility to infections and development of reactions to the drug. Our report discusses a case of a cutaneous reaction to the use of ustekinumab in a 27 year-old male patient after the third dose of the medication. No similar case has been reported in the literature.http://www.pagepress.org/journals/index.php/dr/article/view/4976psoriasis, ustekinumab, late adverse skin reactions |
| spellingShingle | Marina Resener Morais Luana Pizarro Meneghello Carina Flores de Oliveira André Vicente Esteves Carvalho Late reaction to ustekinumab infusion Dermatology Reports psoriasis, ustekinumab, late adverse skin reactions |
| title | Late reaction to ustekinumab infusion |
| title_full | Late reaction to ustekinumab infusion |
| title_fullStr | Late reaction to ustekinumab infusion |
| title_full_unstemmed | Late reaction to ustekinumab infusion |
| title_short | Late reaction to ustekinumab infusion |
| title_sort | late reaction to ustekinumab infusion |
| topic | psoriasis, ustekinumab, late adverse skin reactions |
| url | http://www.pagepress.org/journals/index.php/dr/article/view/4976 |
| work_keys_str_mv | AT marinaresenermorais latereactiontoustekinumabinfusion AT luanapizarromeneghello latereactiontoustekinumabinfusion AT carinafloresdeoliveira latereactiontoustekinumabinfusion AT andrevicenteestevescarvalho latereactiontoustekinumabinfusion |