Core–Shell Spheroid‐Laden Microgels Crosslinked under Biocompatible Conditions for Probing Cancer‐Stromal Communication

Core–Shell Spheroid‐Laden Microgels Crosslinked under Biocompatible Conditions for Probing Cancer‐Stromal Communication

Multicellular cancer spheroids (MCSs) have emerged as a promising in vitro model that recaptures many features of solid tumours in vivo. To generate cancer spheroids, cells are encapsulated in microgels with high throughput. While the biophysical properties of the cancer spheroid and biomaterial inf...

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Bibliographic Details
Main Authors: Hongjia Zhu, Lianne W.Y. Roode, Aled J. Parry, Nadia A. Erkamp, Marc Rodriguez-Garcia, Masako Narita, Yi Shen, Yangteng Ou, Zenon Toprakcioglu, Masashi Narita, Tuomas P.J. Knowles
Format: Article
Language:English
Published: Wiley-VCH 2022-12-01
Series:Advanced NanoBiomed Research
Subjects:
3D cultures
cancer stromal interactions
cocultures
micro-mechanics
microscale hydrogels
nanoporous structures
Online Access:https://doi.org/10.1002/anbr.202200138

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