Variants of Genes Involved in Metabolism of Folate among Patients with Breast Cancer: Association of TYMS 3R Allele with Susceptibility to Breast Cancer and Metastasis

Variants of Genes Involved in Metabolism of Folate among Patients with Breast Cancer: Association of TYMS 3R Allele with Susceptibility to Breast Cancer and Metastasis

Background & Objective: Breast cancer (BC) is known to be the most prevalent cancer among women. One-carbon metabolism (OCM) disturbance might play an important role in the etiology of BC. The present study aimed to investigate the thymidylate synthase (TYMS), 5-methyltetrahydrofolate-homocystei...

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Bibliographic Details
Main Authors: Zohreh Rahimi, Maryam Bozorgi Zarini Bozorgi Zarini, Ziba Rahimi, Ebrahim Shakiba, Asad Vaisi-Raygani, Mohammad Taher Moradi, Kheirolah Yari
Format: Article
Language:English
Published: Iranian Society of Pathology 2021-01-01
Series:Iranian Journal of Pathology
Subjects:
breast cancer
thymidylate synthase
methionine synthase
methionine synthase reductase
polymorphism
metastasis
Online Access:https://ijp.iranpath.org/article_46863_ada2366d6e4658b67e4b78b93513586b.pdf

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