Human toxocarosis. Its seroprevalence in the City of La Plata

Toxocara canis is very common in dogs throughout the world. It is the primary cause of visceral larva migrans (VLM) in humans. Soil contaminated with T. canis embryonated eggs is the main source of infection of man. Our objective was to describe Toxocara seroprevalence in humans in the city of La Pl...

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Main Authors: NE Radman, SM Archelli, RD Fonrouge, M del V Guardis, OR Linzitto
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2000-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000300001
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author NE Radman
SM Archelli
RD Fonrouge
M del V Guardis
OR Linzitto
author_facet NE Radman
SM Archelli
RD Fonrouge
M del V Guardis
OR Linzitto
author_sort NE Radman
collection DOAJ
description Toxocara canis is very common in dogs throughout the world. It is the primary cause of visceral larva migrans (VLM) in humans. Soil contaminated with T. canis embryonated eggs is the main source of infection of man. Our objective was to describe Toxocara seroprevalence in humans in the city of La Plata associated with some determinants such asage, presence or absence of clinical manifestations and risk factors. Blood samples were collected at random from 156 patients of different sex and age, with and without clinical symptoms compatible with the disease. The diagnostic technique ELISA test was performed with the Bordier Affinity Products Commercial Kit, using excretory-secretory Toxocara antigen with a sensitivity higher than 90%. The values were positive in 39% of the studied population. In the analysis according to age, the younger group presented significant differences with respect to the older one (Chi-square p<0.05). Positive patients presented clinical symptoms compatible with the disease (84%), and 41% presented some risk factor. The level of positivity obtained indicates a certain risk of being infectes mainly in patients younger than 15 years old. The authors agree that an early identification and treatment of VLM may save a life.
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spelling doaj.art-36a088d81dcb46108f3f1776eba98d852023-09-02T13:53:44ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602000-06-0195328128510.1590/S0074-02762000000300001Human toxocarosis. Its seroprevalence in the City of La PlataNE RadmanSM ArchelliRD FonrougeM del V GuardisOR LinzittoToxocara canis is very common in dogs throughout the world. It is the primary cause of visceral larva migrans (VLM) in humans. Soil contaminated with T. canis embryonated eggs is the main source of infection of man. Our objective was to describe Toxocara seroprevalence in humans in the city of La Plata associated with some determinants such asage, presence or absence of clinical manifestations and risk factors. Blood samples were collected at random from 156 patients of different sex and age, with and without clinical symptoms compatible with the disease. The diagnostic technique ELISA test was performed with the Bordier Affinity Products Commercial Kit, using excretory-secretory Toxocara antigen with a sensitivity higher than 90%. The values were positive in 39% of the studied population. In the analysis according to age, the younger group presented significant differences with respect to the older one (Chi-square p<0.05). Positive patients presented clinical symptoms compatible with the disease (84%), and 41% presented some risk factor. The level of positivity obtained indicates a certain risk of being infectes mainly in patients younger than 15 years old. The authors agree that an early identification and treatment of VLM may save a life.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000300001toxocarosisseroprevalenceLa PlataArgentina
spellingShingle NE Radman
SM Archelli
RD Fonrouge
M del V Guardis
OR Linzitto
Human toxocarosis. Its seroprevalence in the City of La Plata
Memorias do Instituto Oswaldo Cruz
toxocarosis
seroprevalence
La Plata
Argentina
title Human toxocarosis. Its seroprevalence in the City of La Plata
title_full Human toxocarosis. Its seroprevalence in the City of La Plata
title_fullStr Human toxocarosis. Its seroprevalence in the City of La Plata
title_full_unstemmed Human toxocarosis. Its seroprevalence in the City of La Plata
title_short Human toxocarosis. Its seroprevalence in the City of La Plata
title_sort human toxocarosis its seroprevalence in the city of la plata
topic toxocarosis
seroprevalence
La Plata
Argentina
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762000000300001
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AT rdfonrouge humantoxocarosisitsseroprevalenceinthecityoflaplata
AT mdelvguardis humantoxocarosisitsseroprevalenceinthecityoflaplata
AT orlinzitto humantoxocarosisitsseroprevalenceinthecityoflaplata