Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan
Few studies have compared the effectiveness of internet-based cognitive behavior therapy (ICBT) for obsessive-compulsive disorder (OCD) with treatment as usual (TAU). We investigated the effectiveness of guided ICBT for patients with OCD. This prospective, randomized, controlled, assessor-blinded, m...
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-04-01
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| Series: | Internet Interventions |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214782922000227 |
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| author | Kazuki Matsumoto Sayo Hamatani Takuya Makino Jumpei Takahashi Futoshi Suzuki Tomoko Ida Shoko Hamamura Shinichiro Takiguchi Akemi Tomoda Ichiro M. Omori Hirotaka Kosaka Seina Shinno Tomoki Ikai Hiroyuki Hayashi Hiroto Katayama Yuki Shiko Yoshihito Ozawa Yohei Kawasaki Chihiro Sutoh Eiji Shimizu |
| author_facet | Kazuki Matsumoto Sayo Hamatani Takuya Makino Jumpei Takahashi Futoshi Suzuki Tomoko Ida Shoko Hamamura Shinichiro Takiguchi Akemi Tomoda Ichiro M. Omori Hirotaka Kosaka Seina Shinno Tomoki Ikai Hiroyuki Hayashi Hiroto Katayama Yuki Shiko Yoshihito Ozawa Yohei Kawasaki Chihiro Sutoh Eiji Shimizu |
| author_sort | Kazuki Matsumoto |
| collection | DOAJ |
| description | Few studies have compared the effectiveness of internet-based cognitive behavior therapy (ICBT) for obsessive-compulsive disorder (OCD) with treatment as usual (TAU). We investigated the effectiveness of guided ICBT for patients with OCD. This prospective, randomized, controlled, assessor-blinded, multicenter clinical trial was conducted at three facilities in Japan from January 2020 to March 2021. Thirty-one patients with OCD as the primary diagnosis participated in the trial and were randomly assigned to either the intervention group or the control group. The primary outcome was the Yale–Brown obsessive-compulsive scale score; the assessors were blinded. Results of the analysis of covariance among the groups were significantly different between the groups (p < 0.01, effect size Cohen's d = 1.05), indicating the superiority of guided ICBT. The results suggest that guided ICBT is more effective than TAU for treating OCD. RCT registration: UMIN Clinical Trials Registry (UMIN000039375). |
| first_indexed | 2024-12-12T04:47:30Z |
| format | Article |
| id | doaj.art-36a0dc6051c34ff487eb699229cc7ae7 |
| institution | Directory Open Access Journal |
| issn | 2214-7829 |
| language | English |
| last_indexed | 2024-12-12T04:47:30Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Internet Interventions |
| spelling | doaj.art-36a0dc6051c34ff487eb699229cc7ae72022-12-22T00:37:35ZengElsevierInternet Interventions2214-78292022-04-0128100515Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in JapanKazuki Matsumoto0Sayo Hamatani1Takuya Makino2Jumpei Takahashi3Futoshi Suzuki4Tomoko Ida5Shoko Hamamura6Shinichiro Takiguchi7Akemi Tomoda8Ichiro M. Omori9Hirotaka Kosaka10Seina Shinno11Tomoki Ikai12Hiroyuki Hayashi13Hiroto Katayama14Yuki Shiko15Yoshihito Ozawa16Yohei Kawasaki17Chihiro Sutoh18Eiji Shimizu19Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan; Laboratory of Neuropsychology, Institute of Liberal Arts and Science, Kanazawa University, Ishikawa 920-1192, Japan; Corresponding author at: Research Center for Child Mental Development, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8588, Japan.Research Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan; Research Center for Child Mental Development, University of Fukui, Fukui 910-1192, JapanResearch Center for Child Mental Development, University of Fukui, Fukui 910-1192, JapanResearch Center for Child Mental Development, Chiba University, Chiba 260-8588, JapanResearch Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan; Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, JapanDepartment of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, JapanDepartment of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, JapanDepartment of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, JapanResearch Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan; Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, JapanDepartment of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, JapanResearch Center for Child Mental Development, University of Fukui, Fukui 910-1192, Japan; Department of Child Development, United Graduate School of Child Development, University of Fukui, Fukui 910-1193, Japan; Department of Neuropsychiatry, University of Fukui, Fukui 910-1192, JapanDepartment of Integrated Medical Sciences, Graduate School of Medicine, University of Fukui, Fukui 910-1192, Japan; Department of Integrated Advanced Medicine, Graduate School of Medicine, University of Fukui, Fukui 910-1192, JapanDepartment of Primary Health Care, Faculty of Medicine, University of Fukui, Fukui 910-1192, JapanDepartment of Integrated Advanced Medicine, Graduate School of Medicine, University of Fukui, Fukui 910-1192, Japan; Department of Emergency and General Medicine, University of Fukui Hospital, Fukui 910-1192, JapanKokorotokarada Clinic Fukui, Fukui 910-0067, JapanBiostatistics Section Clinical Research Center, Chiba University Hospital, Chiba 260-8677, JapanBiostatistics Section Clinical Research Center, Chiba University Hospital, Chiba 260-8677, JapanBiostatistics Section Clinical Research Center, Chiba University Hospital, Chiba 260-8677, Japan; Faculty of Nursing, Japanese Red Cross College of Nursing, Tokyo 150-0012, JapanDepartment of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba 260-8588, JapanResearch Center for Child Mental Development, Chiba University, Chiba 260-8588, Japan; Department of Cognitive Behavioral Physiology, Graduate School of Medicine, Chiba University, Chiba 260-8588, Japan; Cognitive Behavioral Therapy Center, Chiba University Hospital, Chiba 260-8588, JapanFew studies have compared the effectiveness of internet-based cognitive behavior therapy (ICBT) for obsessive-compulsive disorder (OCD) with treatment as usual (TAU). We investigated the effectiveness of guided ICBT for patients with OCD. This prospective, randomized, controlled, assessor-blinded, multicenter clinical trial was conducted at three facilities in Japan from January 2020 to March 2021. Thirty-one patients with OCD as the primary diagnosis participated in the trial and were randomly assigned to either the intervention group or the control group. The primary outcome was the Yale–Brown obsessive-compulsive scale score; the assessors were blinded. Results of the analysis of covariance among the groups were significantly different between the groups (p < 0.01, effect size Cohen's d = 1.05), indicating the superiority of guided ICBT. The results suggest that guided ICBT is more effective than TAU for treating OCD. RCT registration: UMIN Clinical Trials Registry (UMIN000039375).http://www.sciencedirect.com/science/article/pii/S2214782922000227Cost-effectivenessInternet-based cognitive behavior therapyRandomized controlled trialObsessive-compulsive disroderTreatment as usual |
| spellingShingle | Kazuki Matsumoto Sayo Hamatani Takuya Makino Jumpei Takahashi Futoshi Suzuki Tomoko Ida Shoko Hamamura Shinichiro Takiguchi Akemi Tomoda Ichiro M. Omori Hirotaka Kosaka Seina Shinno Tomoki Ikai Hiroyuki Hayashi Hiroto Katayama Yuki Shiko Yoshihito Ozawa Yohei Kawasaki Chihiro Sutoh Eiji Shimizu Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan Internet Interventions Cost-effectiveness Internet-based cognitive behavior therapy Randomized controlled trial Obsessive-compulsive disroder Treatment as usual |
| title | Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan |
| title_full | Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan |
| title_fullStr | Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan |
| title_full_unstemmed | Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan |
| title_short | Guided internet-based cognitive behavioral therapy for obsessive-compulsive disorder: A multicenter randomized controlled trial in Japan |
| title_sort | guided internet based cognitive behavioral therapy for obsessive compulsive disorder a multicenter randomized controlled trial in japan |
| topic | Cost-effectiveness Internet-based cognitive behavior therapy Randomized controlled trial Obsessive-compulsive disroder Treatment as usual |
| url | http://www.sciencedirect.com/science/article/pii/S2214782922000227 |
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