DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
Altered epigenetics is a feature of cancer but whether these changes occur early in tumour development is unclear. Here, the authors analyse methylation events in breast cancer and adjacent normal pairs, and show that methylation changes in the normal tissue are also found in the tumour, suggesting...
Үндсэн зохиолчид: | , , , , , , , |
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Формат: | Өгүүллэг |
Хэл сонгох: | English |
Хэвлэсэн: |
Nature Portfolio
2016-01-01
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Цуврал: | Nature Communications |
Онлайн хандалт: | https://doi.org/10.1038/ncomms10478 |