Chronic urticaria in adults: state-of-the-art in the new millennium

Chronic urticaria has been explored in several investigative aspects in the new millennium, either as to its pathogenesis, its stand as an autoimmune or auto-reactive disease, the correlation with HLA-linked genetic factors, especially with class II or it...

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Main Authors: Paulo Ricardo Criado, Roberta Facchini Jardim Criado, Celina Wakisaka Maruta, Vitor Manoel Silva dos Reis
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2015-02-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100074&tlng=en
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author Paulo Ricardo Criado
Roberta Facchini Jardim Criado
Celina Wakisaka Maruta
Vitor Manoel Silva dos Reis
author_facet Paulo Ricardo Criado
Roberta Facchini Jardim Criado
Celina Wakisaka Maruta
Vitor Manoel Silva dos Reis
author_sort Paulo Ricardo Criado
collection DOAJ
description Chronic urticaria has been explored in several investigative aspects in the new millennium, either as to its pathogenesis, its stand as an autoimmune or auto-reactive disease, the correlation with HLA-linked genetic factors, especially with class II or its interrelation with the coagulation and fibrinolysis systems. New second-generation antihistamines, which act as good symptomatic drugs, emerged and were commercialized over the last decade. Old and new drugs that may interfere with the pathophysiology of the disease, such as cyclosporine and omalizumab have been developed and used as treatments. The purpose of this article is to describe the current state of knowledge on aspects of chronic urticaria such as, pathophysiology, diagnosis and the current therapeutic approach proposed in the literature.
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spelling doaj.art-36a53aabf11647908a433e6db6a542032022-12-21T19:44:50ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962015-02-01901748910.1590/abd1806-4841.20153509Chronic urticaria in adults: state-of-the-art in the new millenniumPaulo Ricardo CriadoRoberta Facchini Jardim CriadoCelina Wakisaka MarutaVitor Manoel Silva dos ReisChronic urticaria has been explored in several investigative aspects in the new millennium, either as to its pathogenesis, its stand as an autoimmune or auto-reactive disease, the correlation with HLA-linked genetic factors, especially with class II or its interrelation with the coagulation and fibrinolysis systems. New second-generation antihistamines, which act as good symptomatic drugs, emerged and were commercialized over the last decade. Old and new drugs that may interfere with the pathophysiology of the disease, such as cyclosporine and omalizumab have been developed and used as treatments. The purpose of this article is to describe the current state of knowledge on aspects of chronic urticaria such as, pathophysiology, diagnosis and the current therapeutic approach proposed in the literature.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100074&tlng=enAngioedemaBiological factorsColchicineCyclosporineDapsoneImmunosuppressive agentsUrticaria
spellingShingle Paulo Ricardo Criado
Roberta Facchini Jardim Criado
Celina Wakisaka Maruta
Vitor Manoel Silva dos Reis
Chronic urticaria in adults: state-of-the-art in the new millennium
Anais Brasileiros de Dermatologia
Angioedema
Biological factors
Colchicine
Cyclosporine
Dapsone
Immunosuppressive agents
Urticaria
title Chronic urticaria in adults: state-of-the-art in the new millennium
title_full Chronic urticaria in adults: state-of-the-art in the new millennium
title_fullStr Chronic urticaria in adults: state-of-the-art in the new millennium
title_full_unstemmed Chronic urticaria in adults: state-of-the-art in the new millennium
title_short Chronic urticaria in adults: state-of-the-art in the new millennium
title_sort chronic urticaria in adults state of the art in the new millennium
topic Angioedema
Biological factors
Colchicine
Cyclosporine
Dapsone
Immunosuppressive agents
Urticaria
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100074&tlng=en
work_keys_str_mv AT pauloricardocriado chronicurticariainadultsstateoftheartinthenewmillennium
AT robertafacchinijardimcriado chronicurticariainadultsstateoftheartinthenewmillennium
AT celinawakisakamaruta chronicurticariainadultsstateoftheartinthenewmillennium
AT vitormanoelsilvadosreis chronicurticariainadultsstateoftheartinthenewmillennium