Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study
This study is a retrospective analysis using data collected from the Adelphi Paediatric Psoriasis Disease-Specific Programme cross-sectional survey. Despite being treated for their psoriasis, a substantial proportion of paediatric patients presented with moderate (18.3%) or severe (1.3%) disease at...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Medical Journals Sweden
2022-02-01
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| Series: | Acta Dermato-Venereologica |
| Subjects: | |
| Online Access: | https://medicaljournalssweden.se/actadv/article/view/981 |
| _version_ | 1818982101132771328 |
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| author | Marieke M.B. Seyger Matthias Augustin Michael Sticherling Teresa Bachhuber Juanzhi Fang James Hetherington James Lucas Sophie Meakin Craig Richardson Amy S. Paller |
| author_facet | Marieke M.B. Seyger Matthias Augustin Michael Sticherling Teresa Bachhuber Juanzhi Fang James Hetherington James Lucas Sophie Meakin Craig Richardson Amy S. Paller |
| author_sort | Marieke M.B. Seyger |
| collection | DOAJ |
| description | This study is a retrospective analysis using data collected from the Adelphi Paediatric Psoriasis Disease-Specific Programme cross-sectional survey. Despite being treated for their psoriasis, a substantial proportion of paediatric patients presented with moderate (18.3%) or severe (1.3%) disease at sampling; 42.9% and 92.0% had a body surface area (BSA) of >10%, and 38.8% and 100.0% had a Psoriasis Area Severity Index (PASI) score >10, respectively. Overall, 69.9% of patients had only ever been treated with a topical therapy for their psoriasis. For patients with moderate or severe disease at sampling, 16.3% and 14.4% were currently receiving conventional systemics or biologic therapy, respectively. There is a clinical unmet need in this paediatric population; a considerable percentage of patients still experienced moderate or severe disease and persistent psoriasis symptoms, with numerous body areas affected. A significant proportion of patients were undertreated, which may explain the high burden of disease observed.
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| first_indexed | 2024-12-20T17:41:51Z |
| format | Article |
| id | doaj.art-36a55a0d80b34c9faf6b102f7a2a1015 |
| institution | Directory Open Access Journal |
| issn | 0001-5555 1651-2057 |
| language | English |
| last_indexed | 2024-12-20T17:41:51Z |
| publishDate | 2022-02-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Acta Dermato-Venereologica |
| spelling | doaj.art-36a55a0d80b34c9faf6b102f7a2a10152022-12-21T19:31:04ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572022-02-0110210.2340/actadv.v101.981Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence StudyMarieke M.B. Seyger0Matthias AugustinMichael SticherlingTeresa BachhuberJuanzhi FangJames HetheringtonJames LucasSophie MeakinCraig RichardsonAmy S. PallerDepartment of Dermatology, Radboud University Nijmegen Medical Centre, NL-6500 HB Nijmegen, the NetherlandsThis study is a retrospective analysis using data collected from the Adelphi Paediatric Psoriasis Disease-Specific Programme cross-sectional survey. Despite being treated for their psoriasis, a substantial proportion of paediatric patients presented with moderate (18.3%) or severe (1.3%) disease at sampling; 42.9% and 92.0% had a body surface area (BSA) of >10%, and 38.8% and 100.0% had a Psoriasis Area Severity Index (PASI) score >10, respectively. Overall, 69.9% of patients had only ever been treated with a topical therapy for their psoriasis. For patients with moderate or severe disease at sampling, 16.3% and 14.4% were currently receiving conventional systemics or biologic therapy, respectively. There is a clinical unmet need in this paediatric population; a considerable percentage of patients still experienced moderate or severe disease and persistent psoriasis symptoms, with numerous body areas affected. A significant proportion of patients were undertreated, which may explain the high burden of disease observed. https://medicaljournalssweden.se/actadv/article/view/981psoriasispaediatric psoriasispoint-in-time surveyreal-worldclinical characteristicsunmet needs |
| spellingShingle | Marieke M.B. Seyger Matthias Augustin Michael Sticherling Teresa Bachhuber Juanzhi Fang James Hetherington James Lucas Sophie Meakin Craig Richardson Amy S. Paller Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study Acta Dermato-Venereologica psoriasis paediatric psoriasis point-in-time survey real-world clinical characteristics unmet needs |
| title | Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study |
| title_full | Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study |
| title_fullStr | Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study |
| title_full_unstemmed | Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study |
| title_short | Physician-reported Clinical Unmet Needs, Burden and Treatment Patterns of Paediatric Psoriasis Patients: A US and EU Real-world Evidence Study |
| title_sort | physician reported clinical unmet needs burden and treatment patterns of paediatric psoriasis patients a us and eu real world evidence study |
| topic | psoriasis paediatric psoriasis point-in-time survey real-world clinical characteristics unmet needs |
| url | https://medicaljournalssweden.se/actadv/article/view/981 |
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