Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz
Multiple-subject magnetic resonance imaging has been used in phenotyping studies to reduce the total experimental time by simultaneously capturing images of multiple animals using single or multiple radio frequency (RF) coils. However, conventional methods must consider decoupling circuits to minimi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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IEEE
2022-01-01
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| Series: | IEEE Access |
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| Online Access: | https://ieeexplore.ieee.org/document/9795299/ |
| _version_ | 1811332753644322816 |
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| author | Taewoo Nam Donghyuk Kim Minyeong Seo Geunho Im Daniel Hernandez Taekwan Lee Kyoung-Nam Kim |
| author_facet | Taewoo Nam Donghyuk Kim Minyeong Seo Geunho Im Daniel Hernandez Taekwan Lee Kyoung-Nam Kim |
| author_sort | Taewoo Nam |
| collection | DOAJ |
| description | Multiple-subject magnetic resonance imaging has been used in phenotyping studies to reduce the total experimental time by simultaneously capturing images of multiple animals using single or multiple radio frequency (RF) coils. However, conventional methods must consider decoupling circuits to minimize the mutual inductance coupling between RF coils. These decoupling circuits unnecessarily increase the field of view and image acquisition times. In this study, we propose a rotated surface (RS) coil that can generate a uniformly transmitted magnetic field (<inline-formula> <tex-math notation="LaTeX">$\vert \text{B}_{1}^{+}\vert $ </tex-math></inline-formula>) and minimize the distance between coils when used for multiple-animal imaging without decoupling circuits. The RS coil was designed using an electromagnetic (EM) simulation software, and the rotation angle, which creates a uniform <inline-formula> <tex-math notation="LaTeX">$\vert \text{B}_{1}^{+}\vert $ </tex-math></inline-formula>-component, was derived by mathematical calculations. We compared the <inline-formula> <tex-math notation="LaTeX">$\vert \text{B}_{1}^{+}\vert $ </tex-math></inline-formula>-component uniformity produced by RS coils with different rotation angles and a 4-leg high-pass filter birdcage coil in multiple-coil arrays at the same location using EM simulations. The RS coil displayed a uniformity greater than 94% and 84% uniformity when used as a single-channel and multiple-coil array in the central axial plane, respectively. Following the EM simulations, a multiple-mice RS coil array was manufactured, and a bench test was performed to ensure its operation at 400 MHz and for coupling analysis. T<sub>1</sub>-FLASH images of the four phantoms and mice were acquired using a multiple RS coil array in a 9.4-T preclinical MR system. The signal-to-noise ratio and uniformity were measured using the phantom images. |
| first_indexed | 2024-04-13T16:41:43Z |
| format | Article |
| id | doaj.art-36a71a16e85246a1883fb5efac5d62f8 |
| institution | Directory Open Access Journal |
| issn | 2169-3536 |
| language | English |
| last_indexed | 2024-04-13T16:41:43Z |
| publishDate | 2022-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Access |
| spelling | doaj.art-36a71a16e85246a1883fb5efac5d62f82022-12-22T02:39:13ZengIEEEIEEE Access2169-35362022-01-0110662816628910.1109/ACCESS.2022.31831199795299Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHzTaewoo Nam0https://orcid.org/0000-0002-4234-7817Donghyuk Kim1https://orcid.org/0000-0003-1381-3943Minyeong Seo2Geunho Im3Daniel Hernandez4Taekwan Lee5Kyoung-Nam Kim6Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon, Republic of KoreaNeuroscience Research Institute, Gachon University, Incheon, Republic of KoreaNeuroscience Research Institute, Gachon University, Incheon, Republic of KoreaCenter for Neuroscience Imaging Research, Sungkyunkwan University, Suwon, Republic of KoreaNeuroscience Research Institute, Gachon University, Incheon, Republic of KoreaBrain Core Research Facility, Korea Brain Research Institute, Daegu, Republic of KoreaDepartment of Health Sciences and Technology, GAIHST, Gachon University, Incheon, Republic of KoreaMultiple-subject magnetic resonance imaging has been used in phenotyping studies to reduce the total experimental time by simultaneously capturing images of multiple animals using single or multiple radio frequency (RF) coils. However, conventional methods must consider decoupling circuits to minimize the mutual inductance coupling between RF coils. These decoupling circuits unnecessarily increase the field of view and image acquisition times. In this study, we propose a rotated surface (RS) coil that can generate a uniformly transmitted magnetic field (<inline-formula> <tex-math notation="LaTeX">$\vert \text{B}_{1}^{+}\vert $ </tex-math></inline-formula>) and minimize the distance between coils when used for multiple-animal imaging without decoupling circuits. The RS coil was designed using an electromagnetic (EM) simulation software, and the rotation angle, which creates a uniform <inline-formula> <tex-math notation="LaTeX">$\vert \text{B}_{1}^{+}\vert $ </tex-math></inline-formula>-component, was derived by mathematical calculations. We compared the <inline-formula> <tex-math notation="LaTeX">$\vert \text{B}_{1}^{+}\vert $ </tex-math></inline-formula>-component uniformity produced by RS coils with different rotation angles and a 4-leg high-pass filter birdcage coil in multiple-coil arrays at the same location using EM simulations. The RS coil displayed a uniformity greater than 94% and 84% uniformity when used as a single-channel and multiple-coil array in the central axial plane, respectively. Following the EM simulations, a multiple-mice RS coil array was manufactured, and a bench test was performed to ensure its operation at 400 MHz and for coupling analysis. T<sub>1</sub>-FLASH images of the four phantoms and mice were acquired using a multiple RS coil array in a 9.4-T preclinical MR system. The signal-to-noise ratio and uniformity were measured using the phantom images.https://ieeexplore.ieee.org/document/9795299/Rotated surface coilrotation anglemagnetic resonance imagingmultiple-subjectphenotypingradio frequency coil |
| spellingShingle | Taewoo Nam Donghyuk Kim Minyeong Seo Geunho Im Daniel Hernandez Taekwan Lee Kyoung-Nam Kim Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz IEEE Access Rotated surface coil rotation angle magnetic resonance imaging multiple-subject phenotyping radio frequency coil |
| title | Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz |
| title_full | Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz |
| title_fullStr | Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz |
| title_full_unstemmed | Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz |
| title_short | Design of Rotated Surface Coil Array for Multiple-Subject Imaging at 400 MHz |
| title_sort | design of rotated surface coil array for multiple subject imaging at 400 mhz |
| topic | Rotated surface coil rotation angle magnetic resonance imaging multiple-subject phenotyping radio frequency coil |
| url | https://ieeexplore.ieee.org/document/9795299/ |
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