Fatty acid amide hydrolase levels in brain linked with threat-related amygdala activation

Fatty acid amide hydrolase levels in brain linked with threat-related amygdala activation

Background: Preclinical evidence suggests that increasing levels of the major endocannabinoid anandamide decreases anxiety and fear responses potentially through its effects in the amygdala. Here we used neuroimaging to test the hypothesis that lower fatty acid amide hydrolase (FAAH), the main catab...

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Bibliographic Details
Main Authors: Duncan GJ. Green, Duncan J. Westwood, Jinhee Kim, Laura M. Best, Stephen J. Kish, Rachel F. Tyndale, Tina McCluskey, Nancy J. Lobaugh, Isabelle Boileau
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Neuroimage: Reports
Subjects:
FAAH
fMRI BOLD
PET [11C]CURB
Threat
Perceptual face task
Amygdala
Online Access:http://www.sciencedirect.com/science/article/pii/S2666956022000186

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