CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle.

CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle.

Cervical cancer is the fourth common cancer in women resulting worldwide in 266,000 deaths per year. Belonging to the carcinomas, new insights into cervical cancer biology may also have great implications for finding new treatment strategies for other kinds of epithelial cancers. Although the transc...

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Bibliographic Details
Main Authors: Carsten Slotta, Thomas Schlüter, Lucia M Ruiz-Perera, Hussamadin M Kadhim, Tobias Tertel, Elena Henkel, Wolfgang Hübner, Johannes F W Greiner, Thomas Huser, Barbara Kaltschmidt, Christian Kaltschmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5540532?pdf=render

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