FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status
FAPI PET/CT is a novel imaging tool targeting fibroblast activation protein (FAP), with high tumor uptake rate and low background noise. Therefore, the appearance of FAPI PET/CT provides a good tumor-to-background ratio between tumor and non-tumor tissues, which is beneficial to staging, tumor descr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/2/577 |
| _version_ | 1797440595711492096 |
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| author | Zhiming Cheng Shu Wang Shuoyan Xu Bulin Du Xuena Li Yaming Li |
| author_facet | Zhiming Cheng Shu Wang Shuoyan Xu Bulin Du Xuena Li Yaming Li |
| author_sort | Zhiming Cheng |
| collection | DOAJ |
| description | FAPI PET/CT is a novel imaging tool targeting fibroblast activation protein (FAP), with high tumor uptake rate and low background noise. Therefore, the appearance of FAPI PET/CT provides a good tumor-to-background ratio between tumor and non-tumor tissues, which is beneficial to staging, tumor description and detection. Colorectal cancer has the biological characteristics of high expression of FAP, which provides the foundation for targeted FAP imaging. FAPI PET/CT may have a potential role in changing the staging and re-staging of colorectal cancer, monitoring recurrence and treatment management, and improving the prognosis of patients. This review will summarize the application status of FAPI PET/CT in colorectal cancer and provide directions for further application research. |
| first_indexed | 2024-03-09T12:11:34Z |
| format | Article |
| id | doaj.art-36b0e4c712f94251b2cc59852d49d331 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T12:11:34Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-36b0e4c712f94251b2cc59852d49d3312023-11-30T22:51:51ZengMDPI AGJournal of Clinical Medicine2077-03832023-01-0112257710.3390/jcm12020577FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research StatusZhiming Cheng0Shu Wang1Shuoyan Xu2Bulin Du3Xuena Li4Yaming Li5Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang 110001, ChinaDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang 110001, ChinaDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang 110001, ChinaDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang 110001, ChinaDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang 110001, ChinaDepartment of Nuclear Medicine, The First Hospital of China Medical University, Shenyang 110001, ChinaFAPI PET/CT is a novel imaging tool targeting fibroblast activation protein (FAP), with high tumor uptake rate and low background noise. Therefore, the appearance of FAPI PET/CT provides a good tumor-to-background ratio between tumor and non-tumor tissues, which is beneficial to staging, tumor description and detection. Colorectal cancer has the biological characteristics of high expression of FAP, which provides the foundation for targeted FAP imaging. FAPI PET/CT may have a potential role in changing the staging and re-staging of colorectal cancer, monitoring recurrence and treatment management, and improving the prognosis of patients. This review will summarize the application status of FAPI PET/CT in colorectal cancer and provide directions for further application research.https://www.mdpi.com/2077-0383/12/2/577colorectal cancerFAPIFDGPETSUV<sub>max</sub>SUV<sub>mean</sub> |
| spellingShingle | Zhiming Cheng Shu Wang Shuoyan Xu Bulin Du Xuena Li Yaming Li FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status Journal of Clinical Medicine colorectal cancer FAPI FDG PET SUV<sub>max</sub> SUV<sub>mean</sub> |
| title | FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status |
| title_full | FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status |
| title_fullStr | FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status |
| title_full_unstemmed | FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status |
| title_short | FAPI PET/CT in Diagnostic and Treatment Management of Colorectal Cancer: Review of Current Research Status |
| title_sort | fapi pet ct in diagnostic and treatment management of colorectal cancer review of current research status |
| topic | colorectal cancer FAPI FDG PET SUV<sub>max</sub> SUV<sub>mean</sub> |
| url | https://www.mdpi.com/2077-0383/12/2/577 |
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