Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis
Background: Prevalence of major depressive disorder allocated significant contribution of disease burden in developed and developing countries because of involving active and productive age groups and communities in recent decades. Different methods are used to manage and treat this disorder that on...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2015-08-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/4551 |
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| author | Mohammad Moradi-Joo Hesam Ghiasvand Seyed Mansoor Raygani Sahar Mohabbat-Bahar Bita Sadat Zegordi Hamid Ravaghi |
| author_facet | Mohammad Moradi-Joo Hesam Ghiasvand Seyed Mansoor Raygani Sahar Mohabbat-Bahar Bita Sadat Zegordi Hamid Ravaghi |
| author_sort | Mohammad Moradi-Joo |
| collection | DOAJ |
| description | Background: Prevalence of major depressive disorder allocated significant contribution of disease burden in developed and developing countries because of involving active and productive age groups and communities in recent decades. Different methods are used to manage and treat this disorder that one of them is Transcranial Magnetic Stimulation (TMS). The purpose of this study was assessment of safety, effectiveness and cost-effectiveness of Transcranial Magnetic Stimulation and Repetitive Transcranial Magnetic Stimulation (rTMS) technology in treatment of major depressive disorder.
Methods: In order to gather evidence, main databases [Cochrane Library, Centre for Reviews and Dissemination (CRD), PubMed, Scopus, Trip, Embase, Inahta, PsycINFO, Google Scholar] were searched with appropriate keywords and strategies. After quality assessment of studies, consequences of safety and efficacy of the technology were extracted and Stata 12 software was used, if needed, for meta-analysis.
Findings: From a total of 273 studies, 43 studies were entered firstly and 8 studies were selected after final review. The amount of standardised mean difference (SMD) was equal to -0.3 with a %95 confidence interval of -0.82 to 0.23 for rTMS-treated group versus sham group with a substantial rate and significant heterogeneity (P < 0.001, I-Squared = 81.9%).
Conclusion: Repetitive Transcranial Magnetic Stimulation is a method with significant and high safety. On other side, its efficacy, compared to sham group, is not very significant. |
| first_indexed | 2024-03-12T09:12:43Z |
| format | Article |
| id | doaj.art-36b1b731db314402b911edda460c10af |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T09:12:43Z |
| publishDate | 2015-08-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-36b1b731db314402b911edda460c10af2023-09-02T14:54:40ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2015-08-01333368138251886Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-AnalysisMohammad Moradi-Joo0Hesam Ghiasvand1Seyed Mansoor Raygani2Sahar Mohabbat-Bahar3Bita Sadat Zegordi4Hamid Ravaghi5Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranResearch Center for Health Services Management, Institute for Future Studies in Health, Kerman University of Medical Sciences, Kerman, IranPhysical Medicine and Rehabilitation Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranSchool of Psychology and Educational Sciences, Allame Tabatabai University, Tehran, IranFasa Universit of Medical Sciences, Fasa, IranAssociate Professor, Department of Health Service Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, IranBackground: Prevalence of major depressive disorder allocated significant contribution of disease burden in developed and developing countries because of involving active and productive age groups and communities in recent decades. Different methods are used to manage and treat this disorder that one of them is Transcranial Magnetic Stimulation (TMS). The purpose of this study was assessment of safety, effectiveness and cost-effectiveness of Transcranial Magnetic Stimulation and Repetitive Transcranial Magnetic Stimulation (rTMS) technology in treatment of major depressive disorder. Methods: In order to gather evidence, main databases [Cochrane Library, Centre for Reviews and Dissemination (CRD), PubMed, Scopus, Trip, Embase, Inahta, PsycINFO, Google Scholar] were searched with appropriate keywords and strategies. After quality assessment of studies, consequences of safety and efficacy of the technology were extracted and Stata 12 software was used, if needed, for meta-analysis. Findings: From a total of 273 studies, 43 studies were entered firstly and 8 studies were selected after final review. The amount of standardised mean difference (SMD) was equal to -0.3 with a %95 confidence interval of -0.82 to 0.23 for rTMS-treated group versus sham group with a substantial rate and significant heterogeneity (P < 0.001, I-Squared = 81.9%). Conclusion: Repetitive Transcranial Magnetic Stimulation is a method with significant and high safety. On other side, its efficacy, compared to sham group, is not very significant.http://jims.mui.ac.ir/index.php/jims/article/view/4551Major DepressionRepetitive Transcranial Magnetic Stimulation (rTMS)SafetyEfficacy |
| spellingShingle | Mohammad Moradi-Joo Hesam Ghiasvand Seyed Mansoor Raygani Sahar Mohabbat-Bahar Bita Sadat Zegordi Hamid Ravaghi Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis مجله دانشکده پزشکی اصفهان Major Depression Repetitive Transcranial Magnetic Stimulation (rTMS) Safety Efficacy |
| title | Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis |
| title_full | Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis |
| title_fullStr | Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis |
| title_full_unstemmed | Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis |
| title_short | Safety and Efficacy of Transcranial Magnetic Stimulation (TMS) and Repetitive Transcranial Magnetic Stimulation (rTMS) in Treatment of Major Depressive Disorder: Systematic Reviews and Meta-Analysis |
| title_sort | safety and efficacy of transcranial magnetic stimulation tms and repetitive transcranial magnetic stimulation rtms in treatment of major depressive disorder systematic reviews and meta analysis |
| topic | Major Depression Repetitive Transcranial Magnetic Stimulation (rTMS) Safety Efficacy |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/4551 |
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