Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature

Pulmonary mucoepidermoid carcinoma (PMEC) is a rare tumor, particularly in children, and its clinical manifestations vary. When the tumor is small, it may be asymptomatic; however, with larger tumors, patients may present with symptoms such as recurring pneumonia, atelectasis, persistent cough, ches...

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Main Authors: Yuan Huang, Yong Fu, Jing Sun, Bin Xu, Lei Wu, Lan-fang Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1232185/full
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author Yuan Huang
Yuan Huang
Yong Fu
Jing Sun
Bin Xu
Lei Wu
Lei Wu
Lan-fang Tang
Lan-fang Tang
author_facet Yuan Huang
Yuan Huang
Yong Fu
Jing Sun
Bin Xu
Lei Wu
Lei Wu
Lan-fang Tang
Lan-fang Tang
author_sort Yuan Huang
collection DOAJ
description Pulmonary mucoepidermoid carcinoma (PMEC) is a rare tumor, particularly in children, and its clinical manifestations vary. When the tumor is small, it may be asymptomatic; however, with larger tumors, patients may present with symptoms such as recurring pneumonia, atelectasis, persistent cough, chest pain, and even hemoptysis. PMEC appears as an exophytic intrabronchial mass. This study aims to report on the clinical manifestations, imaging findings, treatment approaches, and prognosis of two children diagnosed with PMEC at our hospital between January 2018 and December 2022. The age of onset for both children was 9 years, and the masses were located in the right upper lobe bronchi. Following surgical treatment, both patients showed a good prognosis. In addition, we conducted a comprehensive review of the relevant literature to enhance the overall understanding of PMEC.
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spelling doaj.art-36b2a74207ec461c83371af84a5429af2023-09-13T05:06:26ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-09-011110.3389/fped.2023.12321851232185Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literatureYuan Huang0Yuan Huang1Yong Fu2Jing Sun3Bin Xu4Lei Wu5Lei Wu6Lan-fang Tang7Lan-fang Tang8Department of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Endoscopy Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Endoscopy Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Pulmonology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaDepartment of Endoscopy Center, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, ChinaPulmonary mucoepidermoid carcinoma (PMEC) is a rare tumor, particularly in children, and its clinical manifestations vary. When the tumor is small, it may be asymptomatic; however, with larger tumors, patients may present with symptoms such as recurring pneumonia, atelectasis, persistent cough, chest pain, and even hemoptysis. PMEC appears as an exophytic intrabronchial mass. This study aims to report on the clinical manifestations, imaging findings, treatment approaches, and prognosis of two children diagnosed with PMEC at our hospital between January 2018 and December 2022. The age of onset for both children was 9 years, and the masses were located in the right upper lobe bronchi. Following surgical treatment, both patients showed a good prognosis. In addition, we conducted a comprehensive review of the relevant literature to enhance the overall understanding of PMEC.https://www.frontiersin.org/articles/10.3389/fped.2023.1232185/fullpulmonary mucoepidermoid carcinoma (PMEC)childrenflexible bronchoscopyatelectasissurgery
spellingShingle Yuan Huang
Yuan Huang
Yong Fu
Jing Sun
Bin Xu
Lei Wu
Lei Wu
Lan-fang Tang
Lan-fang Tang
Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature
Frontiers in Pediatrics
pulmonary mucoepidermoid carcinoma (PMEC)
children
flexible bronchoscopy
atelectasis
surgery
title Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature
title_full Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature
title_fullStr Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature
title_full_unstemmed Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature
title_short Pulmonary mucoepidermoid carcinoma in children: two case reports and a review of the literature
title_sort pulmonary mucoepidermoid carcinoma in children two case reports and a review of the literature
topic pulmonary mucoepidermoid carcinoma (PMEC)
children
flexible bronchoscopy
atelectasis
surgery
url https://www.frontiersin.org/articles/10.3389/fped.2023.1232185/full
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