The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China.
<h4>Objective</h4>Related evidences of metabolically unhealthy profile of adults with normal weight are not well characterized in the Chinese population. This is because they cannot be effectively identified by regular measurements (such as body mass index [BMI]). To overcome this gap in...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0248782 |
| _version_ | 1818929072185540608 |
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| author | Ling Fan Jiangwei Qiu Yu Zhao Ting Yin Xiaoxia Li Qingan Wang Jinyun Jing Jiaxing Zhang Faxuan Wang Xiuying Liu Lan Liu Yi Zhao Yuhong Zhang |
| author_facet | Ling Fan Jiangwei Qiu Yu Zhao Ting Yin Xiaoxia Li Qingan Wang Jinyun Jing Jiaxing Zhang Faxuan Wang Xiuying Liu Lan Liu Yi Zhao Yuhong Zhang |
| author_sort | Ling Fan |
| collection | DOAJ |
| description | <h4>Objective</h4>Related evidences of metabolically unhealthy profile of adults with normal weight are not well characterized in the Chinese population. This is because they cannot be effectively identified by regular measurements (such as body mass index [BMI]). To overcome this gap in literature, this study aimed at investigating the association between body composition and metabolically unhealthy profile in Chinese adults with normal weight.<h4>Methods</h4>A total of 5427 individuals with normal-weight were recruited from 15820 people living in Ningxia Hui Autonomous Region in Northwest China. Normal-weight was defined as a BMI of 18.5-23.9 kg/m2. Metabolically unhealthy profile was assessed by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Metabolically unhealthy normal-weight (MUHNW) profile was defined in individuals who had normal weight and at least two cardiometabolic risk factors. Generalized linear model was used to investigate the association between body composition measured by bioelectrical impedance and metabolically unhealthy profile in adults with normal-weight.<h4>Results</h4>The percentage of metabolically unhealthy profile was 35.86% in adults with normal weight. Different MUHNW distributions were found between males and females depending on age. The percentage of the MUHNW profile significantly increased in women after the age of 55, contrary to men. The association between body composition and MUHNW was affected by age and sex. The increased adiposity indices (fat mass index [FMI], visceral fat level [VFL], waist circumference [WCF]), and reduced skeletal muscle mass ratio [SMR] showed significant differences between MUHNW and metabolically healthy with normal weight (MHNW) (p < 0.05).<h4>Conclusion</h4>The distribution of MUHNW differed between ages and sexes. FMI, VFL, WCF and SMR could be responsible for the MUHNW adults, providing a new insight into the potential metabolic risks for the adults with normal weight in China. This directs us in the management of the MUHNW for their early prevention. |
| first_indexed | 2024-12-20T03:38:59Z |
| format | Article |
| id | doaj.art-36b447dfe12441d4a6951e4cb6f6410f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T03:38:59Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-36b447dfe12441d4a6951e4cb6f6410f2022-12-21T19:54:47ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024878210.1371/journal.pone.0248782The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China.Ling FanJiangwei QiuYu ZhaoTing YinXiaoxia LiQingan WangJinyun JingJiaxing ZhangFaxuan WangXiuying LiuLan LiuYi ZhaoYuhong Zhang<h4>Objective</h4>Related evidences of metabolically unhealthy profile of adults with normal weight are not well characterized in the Chinese population. This is because they cannot be effectively identified by regular measurements (such as body mass index [BMI]). To overcome this gap in literature, this study aimed at investigating the association between body composition and metabolically unhealthy profile in Chinese adults with normal weight.<h4>Methods</h4>A total of 5427 individuals with normal-weight were recruited from 15820 people living in Ningxia Hui Autonomous Region in Northwest China. Normal-weight was defined as a BMI of 18.5-23.9 kg/m2. Metabolically unhealthy profile was assessed by the National Cholesterol Education Program Adult Treatment Panel III (ATP III). Metabolically unhealthy normal-weight (MUHNW) profile was defined in individuals who had normal weight and at least two cardiometabolic risk factors. Generalized linear model was used to investigate the association between body composition measured by bioelectrical impedance and metabolically unhealthy profile in adults with normal-weight.<h4>Results</h4>The percentage of metabolically unhealthy profile was 35.86% in adults with normal weight. Different MUHNW distributions were found between males and females depending on age. The percentage of the MUHNW profile significantly increased in women after the age of 55, contrary to men. The association between body composition and MUHNW was affected by age and sex. The increased adiposity indices (fat mass index [FMI], visceral fat level [VFL], waist circumference [WCF]), and reduced skeletal muscle mass ratio [SMR] showed significant differences between MUHNW and metabolically healthy with normal weight (MHNW) (p < 0.05).<h4>Conclusion</h4>The distribution of MUHNW differed between ages and sexes. FMI, VFL, WCF and SMR could be responsible for the MUHNW adults, providing a new insight into the potential metabolic risks for the adults with normal weight in China. This directs us in the management of the MUHNW for their early prevention.https://doi.org/10.1371/journal.pone.0248782 |
| spellingShingle | Ling Fan Jiangwei Qiu Yu Zhao Ting Yin Xiaoxia Li Qingan Wang Jinyun Jing Jiaxing Zhang Faxuan Wang Xiuying Liu Lan Liu Yi Zhao Yuhong Zhang The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China. PLoS ONE |
| title | The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China. |
| title_full | The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China. |
| title_fullStr | The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China. |
| title_full_unstemmed | The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China. |
| title_short | The association between body composition and metabolically unhealthy profile of adults with normal weight in Northwest China. |
| title_sort | association between body composition and metabolically unhealthy profile of adults with normal weight in northwest china |
| url | https://doi.org/10.1371/journal.pone.0248782 |
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