Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty
We investigated whether chronic stress applied from prepuberty to full sexual maturity interferes with spermatogenic and androgenic testicular functions. Male Wistar rats (40 days old) were immobilized 6 h a day for 60 days. Following immobilization, plasma concentrations of corticosterone and prola...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
1998-01-01
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| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001100013 |
| _version_ | 1811309172429422592 |
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| author | Almeida S.A. Petenusci S.O. Anselmo-Franci J.A. Rosa-e-Silva A.A.M. Lamano-Carvalho T.L. |
| author_facet | Almeida S.A. Petenusci S.O. Anselmo-Franci J.A. Rosa-e-Silva A.A.M. Lamano-Carvalho T.L. |
| author_sort | Almeida S.A. |
| collection | DOAJ |
| description | We investigated whether chronic stress applied from prepuberty to full sexual maturity interferes with spermatogenic and androgenic testicular functions. Male Wistar rats (40 days old) were immobilized 6 h a day for 60 days. Following immobilization, plasma concentrations of corticosterone and prolactin increased 135% and 48%, respectively, while plasma luteinizing hormone and testosterone presented a significant decrease of 29% and 37%, respectively. Plasma concentration of follicle-stimulating hormone was not altered in stressed rats. Chronic stress reduced the amount of mature spermatids in the testis by 16% and the spermatozoon concentration in the cauda epididymidis by 32%. A 17% reduction in weight and a 42% decrease in DNA content were observed in the seminal vesicle of immobilized rats but not in its fructose content. The growth and secretory activity of the ventral prostate were not altered by chronic stress. |
| first_indexed | 2024-04-13T09:37:37Z |
| format | Article |
| id | doaj.art-36baf4044ac14335ab8a8deaf469c120 |
| institution | Directory Open Access Journal |
| issn | 0100-879X 0034-7310 |
| language | English |
| last_indexed | 2024-04-13T09:37:37Z |
| publishDate | 1998-01-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-36baf4044ac14335ab8a8deaf469c1202022-12-22T02:52:02ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X0034-73101998-01-01311114431448Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepubertyAlmeida S.A.Petenusci S.O.Anselmo-Franci J.A.Rosa-e-Silva A.A.M.Lamano-Carvalho T.L.We investigated whether chronic stress applied from prepuberty to full sexual maturity interferes with spermatogenic and androgenic testicular functions. Male Wistar rats (40 days old) were immobilized 6 h a day for 60 days. Following immobilization, plasma concentrations of corticosterone and prolactin increased 135% and 48%, respectively, while plasma luteinizing hormone and testosterone presented a significant decrease of 29% and 37%, respectively. Plasma concentration of follicle-stimulating hormone was not altered in stressed rats. Chronic stress reduced the amount of mature spermatids in the testis by 16% and the spermatozoon concentration in the cauda epididymidis by 32%. A 17% reduction in weight and a 42% decrease in DNA content were observed in the seminal vesicle of immobilized rats but not in its fructose content. The growth and secretory activity of the ventral prostate were not altered by chronic stress.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001100013immobilizationspermatogenesisLHFSHtestosteroneprolactin |
| spellingShingle | Almeida S.A. Petenusci S.O. Anselmo-Franci J.A. Rosa-e-Silva A.A.M. Lamano-Carvalho T.L. Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty Brazilian Journal of Medical and Biological Research immobilization spermatogenesis LH FSH testosterone prolactin |
| title | Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty |
| title_full | Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty |
| title_fullStr | Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty |
| title_full_unstemmed | Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty |
| title_short | Decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization-induced stress from prepuberty |
| title_sort | decreased spermatogenic and androgenic testicular functions in adult rats submitted to immobilization induced stress from prepuberty |
| topic | immobilization spermatogenesis LH FSH testosterone prolactin |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001100013 |
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