Identification of Aptamer-Binding Sites in Hepatitis C Virus Envelope Glycoprotein E2

Identification of Aptamer-Binding Sites in Hepatitis C Virus Envelope Glycoprotein E2

Hepatitis C Virus (HCV) encodes two envelope glycoproteins, E1 and E2. Our previous work selected a specific aptamer ZE2, which could bind to E2 with high affinity, with a great potential for developing new molecular probes as an early diagnostic reagents or therapeutic drugs targeting HCV. In this...

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Bibliographic Details
Main Authors: Fan Chen, Si-Chong Chen, Jing Zhou, Zhi-De Chen, Fang Chen
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2015-01-01
Series:Iranian Journal of Medical Sciences
Subjects:
Hepatitis C virus
Glycoprotein E2
Aptamer
Binding site
Online Access:http://ijms.sums.ac.ir/index.php/IJMS/article/view/1392

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