Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal
Vivek Pant,1 Suman Baral,2 Gita Sayami,3 Prakash Sayami4 1Department of Biochemistry, 2Endocrinology Unit, Department of Medicine, 3Department of Pathology, 4Manmohan Cardiothoracic vascular and transplant Center, Institute of Medicine (IOM), Tribhuvan University Teaching Hospital (TUTH), Kathmandu,...
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Language: | English |
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Dove Medical Press
2017-08-01
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Series: | International Medical Case Reports Journal |
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Online Access: | https://www.dovepress.com/doege-potter-syndrome-cause-of-nonislet-cell-tumor-hypoglycemia-the-fi-peer-reviewed-article-IMCRJ |
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author | Pant V Baral S Sayami G Sayami P |
author_facet | Pant V Baral S Sayami G Sayami P |
author_sort | Pant V |
collection | DOAJ |
description | Vivek Pant,1 Suman Baral,2 Gita Sayami,3 Prakash Sayami4 1Department of Biochemistry, 2Endocrinology Unit, Department of Medicine, 3Department of Pathology, 4Manmohan Cardiothoracic vascular and transplant Center, Institute of Medicine (IOM), Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal Abstract: Doege–Potter syndrome (DPS), a paraneoplastic syndrome, presents as a hypoinsulinemic hypoglycemia from the ectopic secretion of insulin-like growth factor II from a solitary fibrous tumor which may be intrapleural or extrapleural in origin. We report a case of severe hypoglycemia in a 70-year old female initially admitted for resection of left sided solitary fibrous tumor of pleura. Investigation revealed true hypoglycemia, and DPS was diagnosed. The tumor was completely resected, after which no further hypoglycemic episodes were seen in 2 years follow-up. This is the first case of solitary fibrous tumor of pleura with DPS reported from Nepal. Keywords: insulin-like growth factor II, IGF-II, solitary fibrous tumor, hypoglycemia |
first_indexed | 2024-12-12T05:01:41Z |
format | Article |
id | doaj.art-36c1102fe086420d87427a8d780ddbdb |
institution | Directory Open Access Journal |
issn | 1179-142X |
language | English |
last_indexed | 2024-12-12T05:01:41Z |
publishDate | 2017-08-01 |
publisher | Dove Medical Press |
record_format | Article |
series | International Medical Case Reports Journal |
spelling | doaj.art-36c1102fe086420d87427a8d780ddbdb2022-12-22T00:37:12ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2017-08-01Volume 1027527834255Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from NepalPant VBaral SSayami GSayami PVivek Pant,1 Suman Baral,2 Gita Sayami,3 Prakash Sayami4 1Department of Biochemistry, 2Endocrinology Unit, Department of Medicine, 3Department of Pathology, 4Manmohan Cardiothoracic vascular and transplant Center, Institute of Medicine (IOM), Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal Abstract: Doege–Potter syndrome (DPS), a paraneoplastic syndrome, presents as a hypoinsulinemic hypoglycemia from the ectopic secretion of insulin-like growth factor II from a solitary fibrous tumor which may be intrapleural or extrapleural in origin. We report a case of severe hypoglycemia in a 70-year old female initially admitted for resection of left sided solitary fibrous tumor of pleura. Investigation revealed true hypoglycemia, and DPS was diagnosed. The tumor was completely resected, after which no further hypoglycemic episodes were seen in 2 years follow-up. This is the first case of solitary fibrous tumor of pleura with DPS reported from Nepal. Keywords: insulin-like growth factor II, IGF-II, solitary fibrous tumor, hypoglycemiahttps://www.dovepress.com/doege-potter-syndrome-cause-of-nonislet-cell-tumor-hypoglycemia-the-fi-peer-reviewed-article-IMCRJinsulin-like growth factor II (IGF-II)solitary fibrous tumorhypoglycemia |
spellingShingle | Pant V Baral S Sayami G Sayami P Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal International Medical Case Reports Journal insulin-like growth factor II (IGF-II) solitary fibrous tumor hypoglycemia |
title | Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal |
title_full | Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal |
title_fullStr | Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal |
title_full_unstemmed | Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal |
title_short | Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal |
title_sort | doege ndash potter syndrome cause of nonislet cell tumor hypoglycemia the first case report from nepal |
topic | insulin-like growth factor II (IGF-II) solitary fibrous tumor hypoglycemia |
url | https://www.dovepress.com/doege-potter-syndrome-cause-of-nonislet-cell-tumor-hypoglycemia-the-fi-peer-reviewed-article-IMCRJ |
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