Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model

Laxative Effect of Spicatoside A by Cholinergic Regulation of Enteric Nerve in Loperamide-Induced Constipation: ICR Mice Model

Researches on spicatoside A (SpiA)-containing natural products suggest the possibility of SpiA as a potential laxative to alleviate chronic constipation. However, no studies have been conducted with single compound administration of SpiA. To verify the laxative effects and mechanism of action of Spi...

Full description

Bibliographic Details
Main Authors: Ji Eun Kim, Ji Won Park, Mi Ju Kang, Hyeon Jun Choi, Su Ji Bae, Yusang Choi, Young Ju Lee, Sungbaek Seo, Jin Tae Hong, Dae Youn Hwang
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
spicatoside A
constipation
aquaporin
mucin
muscarinic acetylcholine receptors
gastrin
C-kit
Online Access:http://www.mdpi.com/1420-3049/24/5/896

Internet

http://www.mdpi.com/1420-3049/24/5/896

Similar Items