Ameliorative effects of umbelliferone against acetaminophen-induced hepatic oxidative stress and inflammation in mice

Ameliorative effects of umbelliferone against acetaminophen-induced hepatic oxidative stress and inflammation in mice

Background and purpose: Acetaminophen (APAP) is a commonly used antipyretic and pain reliever that its overdose causes acute liver toxicity. Umbelliferone (UMB) has many pharmacological effects. In this study, the hepatoprotective effect of UMB on acute hepatotoxicity induced by APAP was investigate...

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Bibliographic Details
Main Authors: Saeed Sadeghinejad, Mehrnoosh Mousavi, Leila Zeidooni, Esrafil Mansouri, Shokooh Mohtadi, Mohammad Javad Khodayar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
acetaminophen; hepatotoxicity; inflammation; oxidative stress; umbelliferone.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2024;volume=19;issue=1;spage=83;epage=92;aulast=Sadeghinejad

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