Biopterin metabolism and nitric oxide recoupling in cancer

Biopterin metabolism and nitric oxide recoupling in cancer

Tetrahydrobiopterin is a cofactor necessary for the activity of several enzymes, the most studied of which is nitric oxide synthase. The role of this cofactor-enzyme relationship in vascular biology is well established. Recently, tetrahydrobiopterin metabolism has received increasing attention in th...

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Bibliographic Details
Main Authors:	Gene Chatman Clark, Alan Lai, Aashri Agarwal, Zheng Liu, Xiang-Yang Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Series:	Frontiers in Oncology
Subjects:	tetrahydrobiopterin radiotherapy nitric oxide synthase immunotherapy immunometabolism vascular normalization
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1321326/full

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