Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA

Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA

<p>Abstract</p> <p>Background</p> <p>Proliferation and migration of vascular smooth muscle cells (VSMCs) play a key role in neointimal formation which leads to restenosis of vein graft in venous bypass. STAT-3 is a transcription factor associated with cell proliferation...

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Bibliographic Details
Main Authors: Sun Jiangbin, Zheng Jinhua, Ling Kaitelynne H, Zhao Keyan, Xie Zhongshang, Li Bo, Wang Tiance, Zhu Zhicheng, Patel Amit N, Min Weiping, Liu Kexiang, Zheng Xiufen
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Journal of Translational Medicine
Subjects:
STAT-3, siRNA
vascular smooth muscle cells (VSMCs)
intimal thickening
Online Access:http://www.translational-medicine.com/content/10/1/2

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