Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019
Introduction:Advanced age is an independent risk factor for increased mortality in coronavirus disease-2019 (COVID-19). However, the best method for estimating mortality in elderly patients with COVID-19 is still under debate. We performed this study to assess the shock index (SI) and the modified s...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-02-01
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| Series: | İstanbul Medical Journal |
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| Online Access: |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/nvestigation-of-the-prognostic-values-of-the-shock/58700
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| _version_ | 1797894318320517120 |
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| author | Serdar Yeşiltaş Saadet Öztop Mustafa Günay İsmail Sümer Sedat Akbaş Sinan Yılmaz Özge Pasin Kazım Karaaslan |
| author_facet | Serdar Yeşiltaş Saadet Öztop Mustafa Günay İsmail Sümer Sedat Akbaş Sinan Yılmaz Özge Pasin Kazım Karaaslan |
| author_sort | Serdar Yeşiltaş |
| collection | DOAJ |
| description | Introduction:Advanced age is an independent risk factor for increased mortality in coronavirus disease-2019 (COVID-19). However, the best method for estimating mortality in elderly patients with COVID-19 is still under debate. We performed this study to assess the shock index (SI) and the modified shock index (MSI) for the abovementioned problem.Methods:A retrospective study was conducted including elderly cases (≥65 years) confirmed with COVID-19 who admitted to a tertiary university hospital between March-December 2020. The SI and MSI at the time of the emergency department visits were used to evaluate the intensive care unit admission, ventilator support, septic shock, and 30-day mortality in all patients. The receiver operating characteristic and area under the curve (AUC) were used to measure the overall ability of SI and MSI to predict clinical outcomes.Results:We recruited 334 consecutive COVID-19 patients with a mean age of 75.2±7.3 and an almost equal gender distribution [170 males (50.9%)]. In deceased and surviving patients, the SI was 0.66±0.16 and 0.6±0.1 (p=0.014), while the MSI was 0.95±0.22 and 1.09±0.34 (p=0.003), respectively. In predicting mortality, the AUC of the SI and MSI were 0.590 [95% confidence interval (CI): 0.535 to 0.643] and 0.608 (95% CI: 0.553 to 0.660), respectively.Conclusion:Increased SIs and MSIs are associated with 30-day mortality. SI and MSI can benefit the triage of elderly patients hospitalized for COVID-19. However, it was found that there is no single cut-off value of SI or MSI with optimum accuracy for predicting COVID-19-related clinical outcomes. |
| first_indexed | 2024-04-10T07:07:00Z |
| format | Article |
| id | doaj.art-36cb9952a4db45258e1c76c89839095e |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T07:07:00Z |
| publishDate | 2023-02-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-36cb9952a4db45258e1c76c89839095e2023-02-27T05:59:15ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2023-02-01241657010.4274/imj.galenos.2023.4438013049054Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019Serdar Yeşiltaş0Saadet Öztop1Mustafa Günay2İsmail Sümer3Sedat Akbaş4Sinan Yılmaz5Özge Pasin6Kazım Karaaslan7 Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Biostatistics and Medical Informatics, İstanbul, Turkey Bezmialem Vakıf University Faculty of Medicine, Department of Anesthesiology and Reanimation, İstanbul, Turkey Introduction:Advanced age is an independent risk factor for increased mortality in coronavirus disease-2019 (COVID-19). However, the best method for estimating mortality in elderly patients with COVID-19 is still under debate. We performed this study to assess the shock index (SI) and the modified shock index (MSI) for the abovementioned problem.Methods:A retrospective study was conducted including elderly cases (≥65 years) confirmed with COVID-19 who admitted to a tertiary university hospital between March-December 2020. The SI and MSI at the time of the emergency department visits were used to evaluate the intensive care unit admission, ventilator support, septic shock, and 30-day mortality in all patients. The receiver operating characteristic and area under the curve (AUC) were used to measure the overall ability of SI and MSI to predict clinical outcomes.Results:We recruited 334 consecutive COVID-19 patients with a mean age of 75.2±7.3 and an almost equal gender distribution [170 males (50.9%)]. In deceased and surviving patients, the SI was 0.66±0.16 and 0.6±0.1 (p=0.014), while the MSI was 0.95±0.22 and 1.09±0.34 (p=0.003), respectively. In predicting mortality, the AUC of the SI and MSI were 0.590 [95% confidence interval (CI): 0.535 to 0.643] and 0.608 (95% CI: 0.553 to 0.660), respectively.Conclusion:Increased SIs and MSIs are associated with 30-day mortality. SI and MSI can benefit the triage of elderly patients hospitalized for COVID-19. However, it was found that there is no single cut-off value of SI or MSI with optimum accuracy for predicting COVID-19-related clinical outcomes. http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/nvestigation-of-the-prognostic-values-of-the-shock/58700 covid-19modified shock indexmortalityshock indexseptic shock |
| spellingShingle | Serdar Yeşiltaş Saadet Öztop Mustafa Günay İsmail Sümer Sedat Akbaş Sinan Yılmaz Özge Pasin Kazım Karaaslan Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019 İstanbul Medical Journal covid-19 modified shock index mortality shock index septic shock |
| title | Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019 |
| title_full | Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019 |
| title_fullStr | Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019 |
| title_full_unstemmed | Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019 |
| title_short | Investigation of the Prognostic Values of the Shock Index and Modified Shock Index in Predicting the Clinical Outcomes in Elderly Hospitalized Patients with Coronavirus Disease-2019 |
| title_sort | investigation of the prognostic values of the shock index and modified shock index in predicting the clinical outcomes in elderly hospitalized patients with coronavirus disease 2019 |
| topic | covid-19 modified shock index mortality shock index septic shock |
| url |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/nvestigation-of-the-prognostic-values-of-the-shock/58700
|
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