Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures
E-cigarette, or vaping, product use–associated lung injury (EVALI) outbreak was linked to vitamin E acetate (VEA) used as a solvent for tetrahydrocannabinol (THC). Several studies were conducted to assess the products of VEA (and THC/VEA mixtures) thermal degradation as a result of vaporizing/aeroso...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6304/10/2/88 |
| _version_ | 1797476246859284480 |
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| author | Vladimir B. Mikheev Alexander Ivanov |
| author_facet | Vladimir B. Mikheev Alexander Ivanov |
| author_sort | Vladimir B. Mikheev |
| collection | DOAJ |
| description | E-cigarette, or vaping, product use–associated lung injury (EVALI) outbreak was linked to vitamin E acetate (VEA) used as a solvent for tetrahydrocannabinol (THC). Several studies were conducted to assess the products of VEA (and THC/VEA mixtures) thermal degradation as a result of vaporizing/aerosolizing from a traditional type (coil—cotton wick) and ceramic type coil vape pens. The particle size distribution (PSD) of VEA aerosol and the temperature VEA and THC/VEA mixtures are heated to were also measured for a few types of traditional and ceramic vape pens. The current study assessed the PSD of the aerosol generated from THC, VEA, and a number of THC/VEA mixtures using a dab-type vape pen under two different temperature settings and two puffing flow rates. Thermal degradation of THC, VEA, and THC/VEA mixtures were also assessed, and coil temperature was measured. Results showed the dependence of the PSD upon the chemical content of the aerosolized mixture as well as upon the puffing flow rate. Minimal thermal degradation was observed. Flaws in the vape pen’s design, which most likely affected results, were detected. The suitability of VEA, THC, and THC/VEA mixtures with certain types of vape pens was discussed. |
| first_indexed | 2024-03-09T20:56:15Z |
| format | Article |
| id | doaj.art-36d4e6b7e8494221994efea2d8e1ae5a |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-09T20:56:15Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-36d4e6b7e8494221994efea2d8e1ae5a2023-11-23T22:20:36ZengMDPI AGToxics2305-63042022-02-011028810.3390/toxics10020088Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their MixturesVladimir B. Mikheev0Alexander Ivanov1Battelle Memorial Institute, 505 King Avenue, Columbus, OH 43201, USABattelle Memorial Institute, 505 King Avenue, Columbus, OH 43201, USAE-cigarette, or vaping, product use–associated lung injury (EVALI) outbreak was linked to vitamin E acetate (VEA) used as a solvent for tetrahydrocannabinol (THC). Several studies were conducted to assess the products of VEA (and THC/VEA mixtures) thermal degradation as a result of vaporizing/aerosolizing from a traditional type (coil—cotton wick) and ceramic type coil vape pens. The particle size distribution (PSD) of VEA aerosol and the temperature VEA and THC/VEA mixtures are heated to were also measured for a few types of traditional and ceramic vape pens. The current study assessed the PSD of the aerosol generated from THC, VEA, and a number of THC/VEA mixtures using a dab-type vape pen under two different temperature settings and two puffing flow rates. Thermal degradation of THC, VEA, and THC/VEA mixtures were also assessed, and coil temperature was measured. Results showed the dependence of the PSD upon the chemical content of the aerosolized mixture as well as upon the puffing flow rate. Minimal thermal degradation was observed. Flaws in the vape pen’s design, which most likely affected results, were detected. The suitability of VEA, THC, and THC/VEA mixtures with certain types of vape pens was discussed.https://www.mdpi.com/2305-6304/10/2/88e-cigarettevapingproduct use–associated lung injury (EVALI)tetrahydrocannabinol (THC)vitamin E acetate (VEA)thermal degradation |
| spellingShingle | Vladimir B. Mikheev Alexander Ivanov Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures Toxics e-cigarette vaping product use–associated lung injury (EVALI) tetrahydrocannabinol (THC) vitamin E acetate (VEA) thermal degradation |
| title | Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures |
| title_full | Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures |
| title_fullStr | Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures |
| title_full_unstemmed | Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures |
| title_short | Analysis of the Aerosol Generated from Tetrahydrocannabinol, Vitamin E Acetate, and Their Mixtures |
| title_sort | analysis of the aerosol generated from tetrahydrocannabinol vitamin e acetate and their mixtures |
| topic | e-cigarette vaping product use–associated lung injury (EVALI) tetrahydrocannabinol (THC) vitamin E acetate (VEA) thermal degradation |
| url | https://www.mdpi.com/2305-6304/10/2/88 |
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