The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome

Introduction: Obstructive sleep apnea syndrome (OSAS) is a clinical condition characterised by repeated periods of partial or full obstruction of airflow throughout sleep, with impairment of the quality of life and increased mortality with socioeconomic impacts. CPAP therapy is a simple and effectiv...

Full description

Bibliographic Details
Main Authors: Ahmed Ehab, Axel T. Kempa, Harald Englert, Shaza Almasri Bittar, Aida M. Yousef, Heba Wagih Abdelwahab
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Advances in Respiratory Medicine
Subjects:
Online Access:https://www.mdpi.com/2543-6031/91/6/42
_version_ 1797382086416400384
author Ahmed Ehab
Axel T. Kempa
Harald Englert
Shaza Almasri Bittar
Aida M. Yousef
Heba Wagih Abdelwahab
author_facet Ahmed Ehab
Axel T. Kempa
Harald Englert
Shaza Almasri Bittar
Aida M. Yousef
Heba Wagih Abdelwahab
author_sort Ahmed Ehab
collection DOAJ
description Introduction: Obstructive sleep apnea syndrome (OSAS) is a clinical condition characterised by repeated periods of partial or full obstruction of airflow throughout sleep, with impairment of the quality of life and increased mortality with socioeconomic impacts. CPAP therapy is a simple and effective treatment option for OSAS patients. To overcome the clinical and prognostic limitations of AHI—as a sole index of OSAS—the Baveno classification was recently set out and introduced into clinical practice. This study aims to analyse the effect of the Baveno classification on the optimum CPAP titration pressure. Methods: A retrospective analysis of the records of sleep studies in two centres between 2018 and 2021 was carried out. Patients diagnosed with OSAS and recruited for CPAP titration were included. Based on the Baveno classification, the patients were categorised into four groups (A, B, C, and D). Results: Consequently, 700 patients were analysed and 427 patients were included. A significant positive correlation was detected between the CPAP optimum titration pressure and OSAS severity, neck circumference, the oxygen desaturation index (ODI), mean oxygen saturation, the AHI, the BMI, and cumulative sleep time when the SpO<sub>2</sub> was <90% (T90) on the other side (<i>p</i>: <0.0001). A non-significant correlation was seen between the Epworth Sleepiness Scale (ESS), symptom severity, end organ impact, and Baveno classification of the CPAP optimum titration pressure (<i>p</i>: 0.8, 0.4, 0.5, and 0.7, respectively). Conclusions: The Baveno classification is not useful in the prediction of CPAP optimum titration pressure. However, the ODI and neck circumference were significant independent predictors of a higher CPAP titration pressure.
first_indexed 2024-03-08T21:00:24Z
format Article
id doaj.art-36d5e48b934245ea9e34e200099a570c
institution Directory Open Access Journal
issn 2543-6031
language English
last_indexed 2024-03-08T21:00:24Z
publishDate 2023-12-01
publisher MDPI AG
record_format Article
series Advances in Respiratory Medicine
spelling doaj.art-36d5e48b934245ea9e34e200099a570c2023-12-22T13:52:25ZengMDPI AGAdvances in Respiratory Medicine2543-60312023-12-0191657157910.3390/arm91060042The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea SyndromeAhmed Ehab0Axel T. Kempa1Harald Englert2Shaza Almasri Bittar3Aida M. Yousef4Heba Wagih Abdelwahab5Pulmonary Medicine Department, Loewenstein Lung Center, 74245 Loewenstein, GermanyPulmonary Medicine Department, Loewenstein Lung Center, 74245 Loewenstein, GermanyPulmonary Medicine Department, Loewenstein Lung Center, 74245 Loewenstein, GermanyPulmonary Medicine Department, Loewenstein Lung Center, 74245 Loewenstein, GermanyChest Medicine Department, Mansoura University, Mansoura 35511, EgyptChest Medicine Department, Mansoura University, Mansoura 35511, EgyptIntroduction: Obstructive sleep apnea syndrome (OSAS) is a clinical condition characterised by repeated periods of partial or full obstruction of airflow throughout sleep, with impairment of the quality of life and increased mortality with socioeconomic impacts. CPAP therapy is a simple and effective treatment option for OSAS patients. To overcome the clinical and prognostic limitations of AHI—as a sole index of OSAS—the Baveno classification was recently set out and introduced into clinical practice. This study aims to analyse the effect of the Baveno classification on the optimum CPAP titration pressure. Methods: A retrospective analysis of the records of sleep studies in two centres between 2018 and 2021 was carried out. Patients diagnosed with OSAS and recruited for CPAP titration were included. Based on the Baveno classification, the patients were categorised into four groups (A, B, C, and D). Results: Consequently, 700 patients were analysed and 427 patients were included. A significant positive correlation was detected between the CPAP optimum titration pressure and OSAS severity, neck circumference, the oxygen desaturation index (ODI), mean oxygen saturation, the AHI, the BMI, and cumulative sleep time when the SpO<sub>2</sub> was <90% (T90) on the other side (<i>p</i>: <0.0001). A non-significant correlation was seen between the Epworth Sleepiness Scale (ESS), symptom severity, end organ impact, and Baveno classification of the CPAP optimum titration pressure (<i>p</i>: 0.8, 0.4, 0.5, and 0.7, respectively). Conclusions: The Baveno classification is not useful in the prediction of CPAP optimum titration pressure. However, the ODI and neck circumference were significant independent predictors of a higher CPAP titration pressure.https://www.mdpi.com/2543-6031/91/6/42obstructive sleep apnea syndromeapnea–hypopnea indexcontinuous positive airway pressureBaveno classification
spellingShingle Ahmed Ehab
Axel T. Kempa
Harald Englert
Shaza Almasri Bittar
Aida M. Yousef
Heba Wagih Abdelwahab
The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome
Advances in Respiratory Medicine
obstructive sleep apnea syndrome
apnea–hypopnea index
continuous positive airway pressure
Baveno classification
title The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome
title_full The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome
title_fullStr The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome
title_full_unstemmed The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome
title_short The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome
title_sort baveno classification as a predictor of cpap titration pressure in obstructive sleep apnea syndrome
topic obstructive sleep apnea syndrome
apnea–hypopnea index
continuous positive airway pressure
Baveno classification
url https://www.mdpi.com/2543-6031/91/6/42
work_keys_str_mv AT ahmedehab thebavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT axeltkempa thebavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT haraldenglert thebavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT shazaalmasribittar thebavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT aidamyousef thebavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT hebawagihabdelwahab thebavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT ahmedehab bavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT axeltkempa bavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT haraldenglert bavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT shazaalmasribittar bavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT aidamyousef bavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome
AT hebawagihabdelwahab bavenoclassificationasapredictorofcpaptitrationpressureinobstructivesleepapneasyndrome