Doxorubicin-enriched, ALDH<sup>br</sup> mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1

Doxorubicin-enriched, ALDH<sup>br</sup> mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1

<p>Abstract</p> <p>Background</p> <p>The primary objective of this study was to test whether oncolytic herpes simplex virus type 1 (HSV1) could eradicate chemoresistant cancer stem cells (CSCs).</p> <p>Methods</p> <p>The fluorescent aldefluor rea...

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Bibliographic Details
Main Authors: Zhuang Xiufen, Zhang Wen, Chen Yatong, Han Xiangping, Li Jie, Zhang Yu, Zhang Youhui, Zhang Shuren, Liu Binlei
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Cancer
Subjects:
Cancer stem cells
Breast cancer
Chemoresistant
ALDH
Oncolytic virus
Doxorubicin
Herpes simplex virus
Online Access:http://www.biomedcentral.com/1471-2407/12/549

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