A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit
The aim of this study was to determine the rate of health care-associated infection (HC-AI) and device-associated health care-associated infections (DA-HAIs), and distribution of causative microorganisms and etiologic factors responsible for these infections in a neonatal intensive care unit (NICU)...
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| Format: | Article |
| Language: | English |
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Elsevier
2013-10-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957213000478 |
| _version_ | 1828181175205625856 |
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| author | Recep Tekin Tuba Dal Habibe Pirinccioglu Seyhan Erisir Oygucu |
| author_facet | Recep Tekin Tuba Dal Habibe Pirinccioglu Seyhan Erisir Oygucu |
| author_sort | Recep Tekin |
| collection | DOAJ |
| description | The aim of this study was to determine the rate of health care-associated infection (HC-AI) and device-associated health care-associated infections (DA-HAIs), and distribution of causative microorganisms and etiologic factors responsible for these infections in a neonatal intensive care unit (NICU) of a state hospital in southeastern Turkey.
Methods: A laboratory-based, active, prospective nosocomial infection surveillance study was performed in NICUs from January 2008 to December 2011. The rates of HC-AIs were determined on a daily basis. The findings were evaluated by applying the definitions of the Centers for Disease Control and Prevention National Healthcare Safety Network.
Results: In a 4-year period, 580 HC-AIs, 81 of which were DA-HAIs, were detected among 6932 patients. The rate of hospital acquired infection was 8.3% and 7.69/1000 patient days. Ventilator-associated pneumonia (VAP) was the second most frequent (13.1%) HC-AI and the most frequent was DA-HAI. The VAP rate was 6.4 per 1000 ventilator days. Mechanical ventilation was the most frequently used invasive device. Median time to diagnosis of VAP was 32.11 ± 29.3 days from the time of admission. Acinetobacter baumannii (48%) and Pseudomonas aeruginosa (32%) were the most frequent microorganisms. Colistin was the most effective antibiotic by in vitro test. The antibiotic resistance ratios of A. baumannii were ≥54% for carbapenems, aminoglycosides, and cefoperazone–sulbactam; ≥88% for quinolones; and ≥92% for ceftazidime, ceftriaxone, and piperacillin–tazobactam.
Conclusions: Device-associated nosocomial infections was a particularly important problem in NICU. Close monitoring will decrease the rates of device-related nosocomial infections. |
| first_indexed | 2024-04-12T05:56:56Z |
| format | Article |
| id | doaj.art-36d894d52eca423eb73bfdd4c5c124b5 |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-04-12T05:56:56Z |
| publishDate | 2013-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-36d894d52eca423eb73bfdd4c5c124b52022-12-22T03:45:07ZengElsevierPediatrics and Neonatology1875-95722013-10-0154530330810.1016/j.pedneo.2013.03.011A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care UnitRecep Tekin0Tuba Dal1Habibe Pirinccioglu2Seyhan Erisir Oygucu3Department of Infectious Disease and Clinical Microbiology, Faculty of Medicine, Dicle University, Diyarbakir, TurkeyDepartment of Clinical Microbiology, Faculty of Medicine, Dicle University, Diyarbakir, TurkeyDepartment of Infectious Disease and Clinical Microbiology, Diyarbakir Children's Hospital, Diyarbakir, TurkeyDepartment of Neonatalogy, Yasam Hospital, Antalya, TurkeyThe aim of this study was to determine the rate of health care-associated infection (HC-AI) and device-associated health care-associated infections (DA-HAIs), and distribution of causative microorganisms and etiologic factors responsible for these infections in a neonatal intensive care unit (NICU) of a state hospital in southeastern Turkey. Methods: A laboratory-based, active, prospective nosocomial infection surveillance study was performed in NICUs from January 2008 to December 2011. The rates of HC-AIs were determined on a daily basis. The findings were evaluated by applying the definitions of the Centers for Disease Control and Prevention National Healthcare Safety Network. Results: In a 4-year period, 580 HC-AIs, 81 of which were DA-HAIs, were detected among 6932 patients. The rate of hospital acquired infection was 8.3% and 7.69/1000 patient days. Ventilator-associated pneumonia (VAP) was the second most frequent (13.1%) HC-AI and the most frequent was DA-HAI. The VAP rate was 6.4 per 1000 ventilator days. Mechanical ventilation was the most frequently used invasive device. Median time to diagnosis of VAP was 32.11 ± 29.3 days from the time of admission. Acinetobacter baumannii (48%) and Pseudomonas aeruginosa (32%) were the most frequent microorganisms. Colistin was the most effective antibiotic by in vitro test. The antibiotic resistance ratios of A. baumannii were ≥54% for carbapenems, aminoglycosides, and cefoperazone–sulbactam; ≥88% for quinolones; and ≥92% for ceftazidime, ceftriaxone, and piperacillin–tazobactam. Conclusions: Device-associated nosocomial infections was a particularly important problem in NICU. Close monitoring will decrease the rates of device-related nosocomial infections.http://www.sciencedirect.com/science/article/pii/S1875957213000478device-associated health care-associated infectionneonatal intensive care unitnosocomial infectionventilator-associated pneumonia |
| spellingShingle | Recep Tekin Tuba Dal Habibe Pirinccioglu Seyhan Erisir Oygucu A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit Pediatrics and Neonatology device-associated health care-associated infection neonatal intensive care unit nosocomial infection ventilator-associated pneumonia |
| title | A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit |
| title_full | A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit |
| title_fullStr | A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit |
| title_full_unstemmed | A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit |
| title_short | A 4-Year Surveillance of Device-associated Nosocomial Infections in a Neonatal Intensive Care Unit |
| title_sort | 4 year surveillance of device associated nosocomial infections in a neonatal intensive care unit |
| topic | device-associated health care-associated infection neonatal intensive care unit nosocomial infection ventilator-associated pneumonia |
| url | http://www.sciencedirect.com/science/article/pii/S1875957213000478 |
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