Silicon breast implants’ texture affecting bacterial biofilm formation
Introduction/Objective. The most important etiologic factors for both, capsular contracture (CC) and breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is subclinical infection, defined as a response of an organism on presence of biofilm on the implant surface. The aim of this resea...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Serbian Medical Society
2022-01-01
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| Series: | Srpski Arhiv za Celokupno Lekarstvo |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0370-8179/2022/0370-81792200065M.pdf |
| _version_ | 1818050150682066944 |
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| author | Marinković Marija Nikolić Jelena Gusman Vera Jovanović Mladen Rašović Predrag |
| author_facet | Marinković Marija Nikolić Jelena Gusman Vera Jovanović Mladen Rašović Predrag |
| author_sort | Marinković Marija |
| collection | DOAJ |
| description | Introduction/Objective. The most important etiologic factors for both, capsular contracture (CC) and breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is subclinical infection, defined as a response of an organism on presence of biofilm on the implant surface. The aim of this research was to examine the possibility of biofilm formation of four different bacteria (Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Ralstonia picketti) on three differently textured silicone breast implants (Siltex, Mentor, pore size 70–150 μm; MESMORsensitive, Polytech, pore size 50–900 μm; and SilkSurface, Motiva pores 13 μm) in vitro. Methods. Samples of silicone breast implant capsules (sized 1 × 1 cm) were divided into three groups according to texture. After sterilization, 30 samples in every group were contaminated with 100 μl of examined bacterial broth, followed by incubation which led to biofilm formation. For testing the capability of biofilm formation, modified technique with microtitar plates described by Stepanović was used. Results. All four examined bacteria (Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Ralstonia picketti) form more biofilm on implants with pore sizes 50–900 μm compared to implants with pore size 70–150 μm and those with 13 μm. Statistical significance was found in biofilm formation on implants with pores 70–150 μm compared to implants with pores 13 μm. The only exception was P. aeuruginosa which did not show significant difference in biofilm formation on implants 70–150 μm and 13 μm. Conclusion. Silicone breast implants with micro and nanotexture should be chosen in order to prevent biofilm formation and possible consequent complications. |
| first_indexed | 2024-12-10T10:48:54Z |
| format | Article |
| id | doaj.art-36d96e1a72a24fe594c697af439b1e7e |
| institution | Directory Open Access Journal |
| issn | 0370-8179 2406-0895 |
| language | English |
| last_indexed | 2024-12-10T10:48:54Z |
| publishDate | 2022-01-01 |
| publisher | Serbian Medical Society |
| record_format | Article |
| series | Srpski Arhiv za Celokupno Lekarstvo |
| spelling | doaj.art-36d96e1a72a24fe594c697af439b1e7e2022-12-22T01:52:04ZengSerbian Medical SocietySrpski Arhiv za Celokupno Lekarstvo0370-81792406-08952022-01-011507-843944410.2298/SARH211012065M0370-81792200065MSilicon breast implants’ texture affecting bacterial biofilm formationMarinković Marija0Nikolić Jelena1Gusman Vera2Jovanović Mladen3Rašović Predrag4University of Novi Sad, Faculty of medicine, Clinical Centre of Vojvodina, Clinic for Plastic and Reconstructive Surgery, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of medicine, Clinical Centre of Vojvodina, Clinic for Plastic and Reconstructive Surgery, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Medicine, Institute for Public Health of Vojvodina, Laboratory for Microbiology, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of medicine, Clinical Centre of Vojvodina, Clinic for Plastic and Reconstructive Surgery, Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Medicine, Clinical Centre of Vojvodina, Clinic for Orthopedic Surgery and Traumatology, Novi Sad, SerbiaIntroduction/Objective. The most important etiologic factors for both, capsular contracture (CC) and breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is subclinical infection, defined as a response of an organism on presence of biofilm on the implant surface. The aim of this research was to examine the possibility of biofilm formation of four different bacteria (Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Ralstonia picketti) on three differently textured silicone breast implants (Siltex, Mentor, pore size 70–150 μm; MESMORsensitive, Polytech, pore size 50–900 μm; and SilkSurface, Motiva pores 13 μm) in vitro. Methods. Samples of silicone breast implant capsules (sized 1 × 1 cm) were divided into three groups according to texture. After sterilization, 30 samples in every group were contaminated with 100 μl of examined bacterial broth, followed by incubation which led to biofilm formation. For testing the capability of biofilm formation, modified technique with microtitar plates described by Stepanović was used. Results. All four examined bacteria (Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Ralstonia picketti) form more biofilm on implants with pore sizes 50–900 μm compared to implants with pore size 70–150 μm and those with 13 μm. Statistical significance was found in biofilm formation on implants with pores 70–150 μm compared to implants with pores 13 μm. The only exception was P. aeuruginosa which did not show significant difference in biofilm formation on implants 70–150 μm and 13 μm. Conclusion. Silicone breast implants with micro and nanotexture should be chosen in order to prevent biofilm formation and possible consequent complications.http://www.doiserbia.nb.rs/img/doi/0370-8179/2022/0370-81792200065M.pdfbiofilmbacterial adhesionprosthesis-related infectionsbreast implantssilicon elastomers |
| spellingShingle | Marinković Marija Nikolić Jelena Gusman Vera Jovanović Mladen Rašović Predrag Silicon breast implants’ texture affecting bacterial biofilm formation Srpski Arhiv za Celokupno Lekarstvo biofilm bacterial adhesion prosthesis-related infections breast implants silicon elastomers |
| title | Silicon breast implants’ texture affecting bacterial biofilm formation |
| title_full | Silicon breast implants’ texture affecting bacterial biofilm formation |
| title_fullStr | Silicon breast implants’ texture affecting bacterial biofilm formation |
| title_full_unstemmed | Silicon breast implants’ texture affecting bacterial biofilm formation |
| title_short | Silicon breast implants’ texture affecting bacterial biofilm formation |
| title_sort | silicon breast implants texture affecting bacterial biofilm formation |
| topic | biofilm bacterial adhesion prosthesis-related infections breast implants silicon elastomers |
| url | http://www.doiserbia.nb.rs/img/doi/0370-8179/2022/0370-81792200065M.pdf |
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