CD151 drives cancer progression depending on integrin α3β1 through EGFR signaling in non-small cell lung cancer

CD151 drives cancer progression depending on integrin α3β1 through EGFR signaling in non-small cell lung cancer

Abstract Background Tetraspanins CD151, a transmembrane 4 superfamily protein, has been identified participating in the initiation of a variety of cancers. However, the precise function of CD151 in non-small cell lung cancer (NSCLC) remains unclear. Here, we addressed the pro-tumoral role of CD151 i...

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Bibliographic Details
Main Authors: Jianjie Zhu, Tingting Cai, Jieqi Zhou, Wenwen Du, Yuanyuan Zeng, Ting Liu, Yulong Fu, Yue Li, Qian Qian, Xiuwei H. Yang, Qinglin Li, Jian-an Huang, Zeyi Liu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CD151
Integrins
EGFR/ErbB2
Proliferation
NSCLC
Online Access:https://doi.org/10.1186/s13046-021-01998-4

Internet

https://doi.org/10.1186/s13046-021-01998-4

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