ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking
The molecular mechanisms mediating nociception are unclear. Here, the authors show that the Activating Transcription Factor 4 (ATF4) is important for the response to heat nociception in mice and ATF4 role in mediating protein trafficking in dorsal root ganglion neurons.
Bibliographic Details
| Main Authors: |
Man-Xiu Xie,
Xian-Ying Cao,
Wei-An Zeng,
Ren-Chun Lai,
Lan Guo,
Jun-Chao Wang,
Yi-Bin Xiao,
Xi Zhang,
Di Chen,
Xian-Guo Liu,
Xiao-Long Zhang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-21731-1
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