Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture
In this study, we report measurements of the adhesion force of a cell sheet made by applying the ninety-degree peel test. The ninety-degree peel test has been applied to general sheet materials and its procedure is defined by the International Standard Organization (ISO). Only a few studies have bee...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Japan Society of Mechanical Engineers
2013-06-01
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| Series: | Journal of Biomechanical Science and Engineering |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jbse/8/2/8_129/_pdf/-char/en |
| _version_ | 1811296746820599808 |
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| author | Kaoru UESUGI Yoshitake AKIYAMA Takayuki HOSHINO Yoshikatsu AKIYAMA Masayuki YAMATO Teruo OKANO Keisuke MORISHIMA |
| author_facet | Kaoru UESUGI Yoshitake AKIYAMA Takayuki HOSHINO Yoshikatsu AKIYAMA Masayuki YAMATO Teruo OKANO Keisuke MORISHIMA |
| author_sort | Kaoru UESUGI |
| collection | DOAJ |
| description | In this study, we report measurements of the adhesion force of a cell sheet made by applying the ninety-degree peel test. The ninety-degree peel test has been applied to general sheet materials and its procedure is defined by the International Standard Organization (ISO). Only a few studies have been able to measure adhesion force of fragile cell sheets because the sheets are easily broken and cannot be fixed to the conventional fixtures of test systems. Additionally, there are no ninety-degree peel test systems which can measure weak forces such as adhesion force of cell sheets. Therefore, we developed a new fixture to hold the sheet in place during measurements of the adhesion force and we also developed a special test system. Our novel fixture is a multi hook type fixture which allows cell sheets to be fixed to the test system without breaking. We successfully measured adhesion force of a cell sheet. |
| first_indexed | 2024-04-13T05:53:52Z |
| format | Article |
| id | doaj.art-36e0e7b6c16e4018a6aeb2ea7e1487d0 |
| institution | Directory Open Access Journal |
| issn | 1880-9863 |
| language | English |
| last_indexed | 2024-04-13T05:53:52Z |
| publishDate | 2013-06-01 |
| publisher | The Japan Society of Mechanical Engineers |
| record_format | Article |
| series | Journal of Biomechanical Science and Engineering |
| spelling | doaj.art-36e0e7b6c16e4018a6aeb2ea7e1487d02022-12-22T02:59:41ZengThe Japan Society of Mechanical EngineersJournal of Biomechanical Science and Engineering1880-98632013-06-018212913810.1299/jbse.8.129jbseMeasuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type FixtureKaoru UESUGI0Yoshitake AKIYAMA1Takayuki HOSHINO2Yoshikatsu AKIYAMA3Masayuki YAMATO4Teruo OKANO5Keisuke MORISHIMA6Department of Mechanical Engineering, Osaka UniversityDepartment of Mechanical Engineering, Osaka UniversityDepartment of Mechanical Engineering, Osaka UniversityInstitute of Advanced BioMedical Engineering and Science, Tokyo Women's Medical UniversityInstitute of Advanced BioMedical Engineering and Science, Tokyo Women's Medical UniversityInstitute of Advanced BioMedical Engineering and Science, Tokyo Women's Medical UniversityDepartment of Mechanical Engineering, Osaka UniversityIn this study, we report measurements of the adhesion force of a cell sheet made by applying the ninety-degree peel test. The ninety-degree peel test has been applied to general sheet materials and its procedure is defined by the International Standard Organization (ISO). Only a few studies have been able to measure adhesion force of fragile cell sheets because the sheets are easily broken and cannot be fixed to the conventional fixtures of test systems. Additionally, there are no ninety-degree peel test systems which can measure weak forces such as adhesion force of cell sheets. Therefore, we developed a new fixture to hold the sheet in place during measurements of the adhesion force and we also developed a special test system. Our novel fixture is a multi hook type fixture which allows cell sheets to be fixed to the test system without breaking. We successfully measured adhesion force of a cell sheet.https://www.jstage.jst.go.jp/article/jbse/8/2/8_129/_pdf/-char/encell sheetadhesion forceadhesion energypeel testfixtureregenerative medicine |
| spellingShingle | Kaoru UESUGI Yoshitake AKIYAMA Takayuki HOSHINO Yoshikatsu AKIYAMA Masayuki YAMATO Teruo OKANO Keisuke MORISHIMA Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture Journal of Biomechanical Science and Engineering cell sheet adhesion force adhesion energy peel test fixture regenerative medicine |
| title | Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture |
| title_full | Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture |
| title_fullStr | Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture |
| title_full_unstemmed | Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture |
| title_short | Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture |
| title_sort | measuring adhesion force of a cell sheet by the ninety degree peel test using a multi hook type fixture |
| topic | cell sheet adhesion force adhesion energy peel test fixture regenerative medicine |
| url | https://www.jstage.jst.go.jp/article/jbse/8/2/8_129/_pdf/-char/en |
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