A Rare Presentation of Adrenal Leiomyoma Arising in a Ganglioneuroma: A Case Report
Leiomyomas are benign tumours of smooth muscle origin and can occur in any part of the body with adrenal gland being an uncommon site. Ganglioneuromas of adrenal gland are benign neural crest-derived tumours. Both of these tumours are usually detected incidentally. Hereby, the authors report an un...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2023-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/18132/61297_CE[Ra1]_F(IS)_PF1(KA_SHU)_PFA(KA_KM)_PN(KM).pdf |
| Summary: | Leiomyomas are benign tumours of smooth muscle origin and can occur in any part of the body with adrenal gland being an
uncommon site. Ganglioneuromas of adrenal gland are benign neural crest-derived tumours. Both of these tumours are usually
detected incidentally. Hereby, the authors report an unusual case of a 31-year-old woman, who presented with paroxysmal attacks
of headache, palpitations and flushing pointing towards a hormone secreting adrenal tumour. However, functional adrenal markers
were normal. Radiological investigations revealed 8×3 cm heterogeneously enhancing left suprarenal mass with calcification and
extension to left renal vein. Patient underwent left nephrectomy and adrenalectomy with a high clinical suspicion of malignancy
because of tumour extension to the renal vein. The histopathological examination revealed a leiomyoma arising in a background of
ganglioneuroma which was later on confirmed using immunohistochemistry. Authors have presented the present case because of
atypical presentation as a hormone secreting adrenal tumour with radiological features of malignancy and the unique histomorphology
of the combined occurrence of leiomyoma and ganglioneuromatous area in the adrenal gland. To the best of author’s knowledge,
this is the first case report of such an occurrence in the adrenal gland.
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| ISSN: | 2249-782X 0973-709X |