The speed-gene study: methods, study design and preliminary results
Abstract The Speed-Gene study aims to identify genetic variants influencing athletic performance and human locomotion using motion capture technology. Currently, 60 female participants have completed the testing protocol, and the overall aim is to recruit 283 moderately trained, healthy Southeast As...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-11-01
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| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13104-023-06617-3 |
| _version_ | 1797454005860827136 |
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| author | Swam Htet Miftahul Zannah Thet Hnin Moe Pongpanot Wongveerakul Nongnapas Charoenpanich Vitoon Saengsirisuwan Ioannis Papadimitriou |
| author_facet | Swam Htet Miftahul Zannah Thet Hnin Moe Pongpanot Wongveerakul Nongnapas Charoenpanich Vitoon Saengsirisuwan Ioannis Papadimitriou |
| author_sort | Swam Htet |
| collection | DOAJ |
| description | Abstract The Speed-Gene study aims to identify genetic variants influencing athletic performance and human locomotion using motion capture technology. Currently, 60 female participants have completed the testing protocol, and the overall aim is to recruit 283 moderately trained, healthy Southeast Asian individuals (18–45 y, BMI < 30). Participants will undergo biomechanical analysis and genetic testing. Several analyses will be performed, including (but not limited to) linear and angular kinematic analysis using motion capture technology, force plate dynamometry and genetic analyses to define novel power/torque related outcomes that would be more sensitive to allele-specific differences in athletic performance. Pretesting beverages will be provided, and activity history and current activity levels will be assessed by a questionnaire. The kinematic data will be obtained using a Qualisys Track Manager (QTM) system, and DNA will be extracted from white blood cells. The participants serve as their own controls. Although the Speed-Gene study is tightly controlled, our preliminary findings still indicate considerable individual variability. More participants and further genetic analysis are required to allow the investigation of potential underlying genetic mechanisms responsible for this individual variability. |
| first_indexed | 2024-03-09T15:31:01Z |
| format | Article |
| id | doaj.art-36e448bb5eef47098f5604152812033b |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-03-09T15:31:01Z |
| publishDate | 2023-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-36e448bb5eef47098f5604152812033b2023-11-26T12:14:29ZengBMCBMC Research Notes1756-05002023-11-011611910.1186/s13104-023-06617-3The speed-gene study: methods, study design and preliminary resultsSwam Htet0Miftahul Zannah1Thet Hnin Moe2Pongpanot Wongveerakul3Nongnapas Charoenpanich4Vitoon Saengsirisuwan5Ioannis Papadimitriou6Department of Physiology, Faculty of Science, Mahidol UniversityDepartment of Physiology, Faculty of Science, Mahidol UniversityDepartment of Physiology, Faculty of Science, Mahidol UniversityDepartment of Physiology, Faculty of Science, Mahidol UniversityHuman Movement Performance Enhancement Research Unit, Faculty of Sports Science, Chulalongkorn UniversityDepartment of Physiology, Faculty of Science, Mahidol UniversityDepartment of Physiology, Faculty of Science, Mahidol UniversityAbstract The Speed-Gene study aims to identify genetic variants influencing athletic performance and human locomotion using motion capture technology. Currently, 60 female participants have completed the testing protocol, and the overall aim is to recruit 283 moderately trained, healthy Southeast Asian individuals (18–45 y, BMI < 30). Participants will undergo biomechanical analysis and genetic testing. Several analyses will be performed, including (but not limited to) linear and angular kinematic analysis using motion capture technology, force plate dynamometry and genetic analyses to define novel power/torque related outcomes that would be more sensitive to allele-specific differences in athletic performance. Pretesting beverages will be provided, and activity history and current activity levels will be assessed by a questionnaire. The kinematic data will be obtained using a Qualisys Track Manager (QTM) system, and DNA will be extracted from white blood cells. The participants serve as their own controls. Although the Speed-Gene study is tightly controlled, our preliminary findings still indicate considerable individual variability. More participants and further genetic analysis are required to allow the investigation of potential underlying genetic mechanisms responsible for this individual variability.https://doi.org/10.1186/s13104-023-06617-3TorquePowerBiomechanicsDNAPhysiology |
| spellingShingle | Swam Htet Miftahul Zannah Thet Hnin Moe Pongpanot Wongveerakul Nongnapas Charoenpanich Vitoon Saengsirisuwan Ioannis Papadimitriou The speed-gene study: methods, study design and preliminary results BMC Research Notes Torque Power Biomechanics DNA Physiology |
| title | The speed-gene study: methods, study design and preliminary results |
| title_full | The speed-gene study: methods, study design and preliminary results |
| title_fullStr | The speed-gene study: methods, study design and preliminary results |
| title_full_unstemmed | The speed-gene study: methods, study design and preliminary results |
| title_short | The speed-gene study: methods, study design and preliminary results |
| title_sort | speed gene study methods study design and preliminary results |
| topic | Torque Power Biomechanics DNA Physiology |
| url | https://doi.org/10.1186/s13104-023-06617-3 |
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