| Summary: | The clinical prognosis of acute severe brain injury is poor, and therapeutic hypothermia in targeted temperature management (TTM) is considered to be one of the most effective neuroprotective methods, which might effectively improve the prognosis of patients. Target temperature management includes therapeutic hypothermia, normal body temperature control and fever therapy. In recent years, there have been more and more studies about the effectiveness of therapeutic hypothermia and the measures toimprove its effectiveness. This article reviews the research progress of targeted temperature management in the treatment of severe neurological diseases, so as to provide a better neuroprotective strategy for the clinic.
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