Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines
Non-polio enteroviruses (NPEVs) are ubiquitous and are one of the main causative agents of viral infections in children. NPEVs most commonly infect newborns and young children, due to their lack of antibodies. In children, clinical manifestations can range from acute febrile illness to severe compli...
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| Format: | Article |
| Language: | English |
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Central Research Institute for Epidemiology
2022-09-01
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| Series: | Вопросы вирусологии |
| Subjects: | |
| Online Access: | https://virusjour.crie.ru/jour/article/viewFile/623/388 |
| _version_ | 1797782261211332608 |
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| author | Dmitri V. Novikov Dmitry A. Melentev |
| author_facet | Dmitri V. Novikov Dmitry A. Melentev |
| author_sort | Dmitri V. Novikov |
| collection | DOAJ |
| description | Non-polio enteroviruses (NPEVs) are ubiquitous and are one of the main causative agents of viral infections in children. NPEVs most commonly infect newborns and young children, due to their lack of antibodies. In children, clinical manifestations can range from acute febrile illness to severe complications that require hospitalization and lead in some cases to disability or death. NPEV infections can have severe consequences, such as polio-like diseases, serous meningitis, meningoencephalitis, myocarditis, etc. The most promising strategy for preventing such diseases is vaccination. No less than 53 types of NPEVs have been found to circulate in Russia. However, of epidemic importance are the causative agents of exanthemic forms of the disease, aseptic meningitis and myocarditis. At the same time, the frequency of NPEV detection in the constituent entities of the Russian Federation is characterized by uneven distribution and seasonal upsurges. The review discusses the epidemic significance of different types of enteroviruses, including those relevant to the Russian Federation, as well as current technologies used to create enterovirus vaccines for the prevention of serious diseases. |
| first_indexed | 2024-03-13T00:08:29Z |
| format | Article |
| id | doaj.art-36e9eb5597304f0dab341c7e084f78e8 |
| institution | Directory Open Access Journal |
| issn | 0507-4088 2411-2097 |
| language | English |
| last_indexed | 2024-03-13T00:08:29Z |
| publishDate | 2022-09-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Вопросы вирусологии |
| spelling | doaj.art-36e9eb5597304f0dab341c7e084f78e82023-07-12T19:33:31ZengCentral Research Institute for EpidemiologyВопросы вирусологии0507-40882411-20972022-09-0167318519210.36233/0507-4088-111439Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccinesDmitri V. Novikov0https://orcid.org/0000-0001-7049-6935Dmitry A. Melentev1https://orcid.org/0000-0002-2441-6874Academician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and MicrobiologyAcademician I.N. Blokhina Nizhny Novgorod Scientific Research Institute of Epidemiology and MicrobiologyNon-polio enteroviruses (NPEVs) are ubiquitous and are one of the main causative agents of viral infections in children. NPEVs most commonly infect newborns and young children, due to their lack of antibodies. In children, clinical manifestations can range from acute febrile illness to severe complications that require hospitalization and lead in some cases to disability or death. NPEV infections can have severe consequences, such as polio-like diseases, serous meningitis, meningoencephalitis, myocarditis, etc. The most promising strategy for preventing such diseases is vaccination. No less than 53 types of NPEVs have been found to circulate in Russia. However, of epidemic importance are the causative agents of exanthemic forms of the disease, aseptic meningitis and myocarditis. At the same time, the frequency of NPEV detection in the constituent entities of the Russian Federation is characterized by uneven distribution and seasonal upsurges. The review discusses the epidemic significance of different types of enteroviruses, including those relevant to the Russian Federation, as well as current technologies used to create enterovirus vaccines for the prevention of serious diseases.https://virusjour.crie.ru/jour/article/viewFile/623/388non-polio enterovirusesvaccinepolio-like diseasesenterovirus infectionvirus-like particles |
| spellingShingle | Dmitri V. Novikov Dmitry A. Melentev Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines Вопросы вирусологии non-polio enteroviruses vaccine polio-like diseases enterovirus infection virus-like particles |
| title | Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines |
| title_full | Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines |
| title_fullStr | Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines |
| title_full_unstemmed | Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines |
| title_short | Enteroviral (<i>Picornaviridae: Enterovirus</i>) (nonpolio) vaccines |
| title_sort | enteroviral i picornaviridae enterovirus i nonpolio vaccines |
| topic | non-polio enteroviruses vaccine polio-like diseases enterovirus infection virus-like particles |
| url | https://virusjour.crie.ru/jour/article/viewFile/623/388 |
| work_keys_str_mv | AT dmitrivnovikov enteroviralipicornaviridaeenterovirusinonpoliovaccines AT dmitryamelentev enteroviralipicornaviridaeenterovirusinonpoliovaccines |