A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity
IgG4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by IgG4-positive plasma cell and T lymphocyte infiltration of multiple organs. It commonly involves the pancreas, lacrimal glands, and salivary glands, and it has been rarely reported in the sinonasal cavity. We herein r...
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| Format: | Article |
| Language: | English |
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Korean Rhinologic Society
2023-03-01
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| Series: | Journal of Rhinology |
| Subjects: | |
| Online Access: | http://j-rhinology.org/upload/pdf/jr-2023-00008.pdf |
| _version_ | 1827964677665062912 |
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| author | Ju Eun Lee Se Hwan Hwang |
| author_facet | Ju Eun Lee Se Hwan Hwang |
| author_sort | Ju Eun Lee |
| collection | DOAJ |
| description | IgG4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by IgG4-positive plasma cell and T lymphocyte infiltration of multiple organs. It commonly involves the pancreas, lacrimal glands, and salivary glands, and it has been rarely reported in the sinonasal cavity. We herein report the case of a 47-year-old male patient whose chief complaint was decreased visual acuity. A tumefactive mass was found on imaging studies, originating from the sinonasal cavity and invading the orbit, kidney, and meninges. The mass was resected through endoscopic sinus surgery and was pathologically confirmed to be IgG4-RD. The patient was treated with steroid therapy and showed clinical improvement. |
| first_indexed | 2024-04-09T17:21:19Z |
| format | Article |
| id | doaj.art-36f1c365bd024276b2c2f256a3753962 |
| institution | Directory Open Access Journal |
| issn | 1229-1498 2384-4361 |
| language | English |
| last_indexed | 2024-04-09T17:21:19Z |
| publishDate | 2023-03-01 |
| publisher | Korean Rhinologic Society |
| record_format | Article |
| series | Journal of Rhinology |
| spelling | doaj.art-36f1c365bd024276b2c2f256a37539622023-04-19T02:25:25ZengKorean Rhinologic SocietyJournal of Rhinology1229-14982384-43612023-03-01301485210.18787/jr.2023.00008777A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual AcuityJu Eun Lee0Se Hwan Hwang Department of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaIgG4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by IgG4-positive plasma cell and T lymphocyte infiltration of multiple organs. It commonly involves the pancreas, lacrimal glands, and salivary glands, and it has been rarely reported in the sinonasal cavity. We herein report the case of a 47-year-old male patient whose chief complaint was decreased visual acuity. A tumefactive mass was found on imaging studies, originating from the sinonasal cavity and invading the orbit, kidney, and meninges. The mass was resected through endoscopic sinus surgery and was pathologically confirmed to be IgG4-RD. The patient was treated with steroid therapy and showed clinical improvement.http://j-rhinology.org/upload/pdf/jr-2023-00008.pdfimmunoglobulin gimmunoglobulin g4-related diseaseparanasal sinusesglucocorticoid |
| spellingShingle | Ju Eun Lee Se Hwan Hwang A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity Journal of Rhinology immunoglobulin g immunoglobulin g4-related disease paranasal sinuses glucocorticoid |
| title | A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity |
| title_full | A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity |
| title_fullStr | A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity |
| title_full_unstemmed | A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity |
| title_short | A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity |
| title_sort | case of igg4 related disease with sinonasal involvement presenting with decreased visual acuity |
| topic | immunoglobulin g immunoglobulin g4-related disease paranasal sinuses glucocorticoid |
| url | http://j-rhinology.org/upload/pdf/jr-2023-00008.pdf |
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