A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction

A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction

Abstract Protein phosphorylation plays an important role in learning and memory. Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase involved in the regulation of neural synaptic plasticity. Here, to determine if PP2A is necessary for successful learning and memory, we have utilized a Tg...

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Bibliographic Details
Main Authors: Jing Wang, Ran Xie, Xiaolin Kou, Yu Liu, Cui Qi, Rui Liu, Weiyan You, Jun Gao, Xiang Gao
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Molecular Brain
Subjects:
PP2A
Extinction
Learning and memory
Synaptic plasticity
Hippocampus
Online Access:http://link.springer.com/article/10.1186/s13041-019-0469-9

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