THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM
Hypothyroidism is a significant aggravating factor for coronary heart disease (CHD). However, there are no practical recommendations for the management of this group to date. The main method of assessing the severity of coronary artery disease is a morphological assessment of the condition of the co...
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| Format: | Article |
| Language: | English |
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Ministry of Health of the Russian Federation, Irkutsk State Medical University
2023-12-01
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| Series: | Байкальский медицинский журнал |
| Subjects: | |
| Online Access: | https://www.bmjour.ru/jour/article/view/175 |
| _version_ | 1797370627101818880 |
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| author | Muneer Abdul Rahman Aleksey N. Sumin Andrey S. Ankudinov |
| author_facet | Muneer Abdul Rahman Aleksey N. Sumin Andrey S. Ankudinov |
| author_sort | Muneer Abdul Rahman |
| collection | DOAJ |
| description | Hypothyroidism is a significant aggravating factor for coronary heart disease (CHD). However, there are no practical recommendations for the management of this group to date. The main method of assessing the severity of coronary artery disease is a morphological assessment of the condition of the coronary arteries.The aim. To carry out comparative assessment of clinical parameters, including the state of the coronary bed in patients with coronary artery disease with newly diagnosed (without hormone replacement therapy) and primary manifest hypothyroidism compared with patients with coronary artery disease without hypothyroidism.Materials and methods. Two hundred and forty patients with CHD were examined. The study group included 90 patients with coronary heart disease and hypothyroidism, the comparison group consisted of 150 patients with coronary artery disease without thyroid pathology. A comprehensive examination of patients, including coronary angiography, was performed. The frequency of cases and characteristics of lesions of the coronary bed, the volume of interventions were assessed. The analysis of the obtained data was carried out in Statistica 10.0 (StatSoft Inc., USA).Results. In the study group (CHD and hypothyroidism), a statistically significantly increased level of myoglobin, a change in lipid profile parameters in relation to patients with CHD without hypothyroidism was found. In the group of patients with coronary artery disease and hypothyroidism, a predominance of the frequency of multivessel lesions of the coronary bed was revealed. The volume of surgical interventions between the examined patients did not reveal significant differences.Conclusion. Patients with coronary heart disease and hypothyroidism should be considered as a group of additional cardiovascular risk and require a more careful approach. It is possible to prescribe higher dosages of statins. |
| first_indexed | 2024-03-08T18:08:22Z |
| format | Article |
| id | doaj.art-36f58716c99a4e8c8d6ea4971e32f5d3 |
| institution | Directory Open Access Journal |
| issn | 2949-0715 |
| language | English |
| last_indexed | 2024-03-08T18:08:22Z |
| publishDate | 2023-12-01 |
| publisher | Ministry of Health of the Russian Federation, Irkutsk State Medical University |
| record_format | Article |
| series | Байкальский медицинский журнал |
| spelling | doaj.art-36f58716c99a4e8c8d6ea4971e32f5d32024-01-01T12:18:06ZengMinistry of Health of the Russian Federation, Irkutsk State Medical UniversityБайкальский медицинский журнал2949-07152023-12-0124647110.57256/2949-0715-2023-4-64-71104THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISMMuneer Abdul Rahman0Aleksey N. Sumin1Andrey S. Ankudinov2Керальский институт медицинских наук; ФГБОУ ВО Иркутский государственный медицинский университет Минздрава РоссииФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний"ФГБОУ ВО Иркутский государственный медицинский университет Минздрава России ОГБУЗ Иркутская городская клиническая больница №1Hypothyroidism is a significant aggravating factor for coronary heart disease (CHD). However, there are no practical recommendations for the management of this group to date. The main method of assessing the severity of coronary artery disease is a morphological assessment of the condition of the coronary arteries.The aim. To carry out comparative assessment of clinical parameters, including the state of the coronary bed in patients with coronary artery disease with newly diagnosed (without hormone replacement therapy) and primary manifest hypothyroidism compared with patients with coronary artery disease without hypothyroidism.Materials and methods. Two hundred and forty patients with CHD were examined. The study group included 90 patients with coronary heart disease and hypothyroidism, the comparison group consisted of 150 patients with coronary artery disease without thyroid pathology. A comprehensive examination of patients, including coronary angiography, was performed. The frequency of cases and characteristics of lesions of the coronary bed, the volume of interventions were assessed. The analysis of the obtained data was carried out in Statistica 10.0 (StatSoft Inc., USA).Results. In the study group (CHD and hypothyroidism), a statistically significantly increased level of myoglobin, a change in lipid profile parameters in relation to patients with CHD without hypothyroidism was found. In the group of patients with coronary artery disease and hypothyroidism, a predominance of the frequency of multivessel lesions of the coronary bed was revealed. The volume of surgical interventions between the examined patients did not reveal significant differences.Conclusion. Patients with coronary heart disease and hypothyroidism should be considered as a group of additional cardiovascular risk and require a more careful approach. It is possible to prescribe higher dosages of statins.https://www.bmjour.ru/jour/article/view/175ишемическая болезнь сердца, гипотиреоз, поражение коронарных артерий |
| spellingShingle | Muneer Abdul Rahman Aleksey N. Sumin Andrey S. Ankudinov THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM Байкальский медицинский журнал ишемическая болезнь сердца, гипотиреоз, поражение коронарных артерий |
| title | THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM |
| title_full | THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM |
| title_fullStr | THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM |
| title_full_unstemmed | THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM |
| title_short | THE STATE OF THE CORONARY BED IN CORONARY HEART DISEASE IN PATIENTS WITH HYPOTHYROIDISM |
| title_sort | state of the coronary bed in coronary heart disease in patients with hypothyroidism |
| topic | ишемическая болезнь сердца, гипотиреоз, поражение коронарных артерий |
| url | https://www.bmjour.ru/jour/article/view/175 |
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