The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease
Abstract Objective This study was performed in Razi Hospital, Rasht, Iran, between March 2016 and August 2018 on a population of chronic obstructive pulmonary disease (COPD) patients (56 as COPD exacerbation group and 56 as COPD stable group). Study variables include age, sex, occupation, body mass...
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| Format: | Article |
| Language: | English |
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BMC
2022-09-01
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| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13104-022-06217-7 |
| _version_ | 1811238705651777536 |
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| author | Behrang Motamed Ali Alavi Foumani Azita Tangestaninezhad Mohammad Almasi Niloofar Faraji Alireza Jafarinezhad |
| author_facet | Behrang Motamed Ali Alavi Foumani Azita Tangestaninezhad Mohammad Almasi Niloofar Faraji Alireza Jafarinezhad |
| author_sort | Behrang Motamed |
| collection | DOAJ |
| description | Abstract Objective This study was performed in Razi Hospital, Rasht, Iran, between March 2016 and August 2018 on a population of chronic obstructive pulmonary disease (COPD) patients (56 as COPD exacerbation group and 56 as COPD stable group). Study variables include age, sex, occupation, body mass index (BMI), cigarette consumption, duration of COPD, annual hospitalization, dyspnea, glycated hemoglobin (HbA1c), FEV1, and FEV1/FVC indices. Result The mean age of the participants was 63.92 ± 10.75 years. There was a significant difference in the hospitalization between the patients with both exacerbation and normal state of COPD (P ≤ 0.001). HbA1c in the patients with exacerbation of COPD was significantly higher than stable status (P = 0.001). Logistic regression showed that HbA1c levels and hospitalization were predictors of exacerbation of COPD. HbA1c levels were statistically significant in terms of hospitalization in patients with COPD exacerbation. There was a significant difference between the HbA1c levels and MMRC in patients with COPD. The percentage of HbA1c was associated with exacerbation of COPD and HbA1c is a good predictor of disease severity in patients with COPD. It also shows that patients with COPD exacerbation and severe COPD are at the higher risk of hyperglycemia. |
| first_indexed | 2024-04-12T12:46:55Z |
| format | Article |
| id | doaj.art-36f649bad2c14b73bc2b066469697dd0 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-12T12:46:55Z |
| publishDate | 2022-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-36f649bad2c14b73bc2b066469697dd02022-12-22T03:32:36ZengBMCBMC Research Notes1756-05002022-09-011511610.1186/s13104-022-06217-7The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary diseaseBehrang Motamed0Ali Alavi Foumani1Azita Tangestaninezhad2Mohammad Almasi3Niloofar Faraji4Alireza Jafarinezhad5Inflammatory Lung Diseases Research Center, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical SciencesInflammatory Lung Diseases Research Center, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical SciencesInflammatory Lung Diseases Research Center, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical SciencesInflammatory Lung Diseases Research Center, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical SciencesRazi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical SciencesInflammatory Lung Diseases Research Center, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical SciencesAbstract Objective This study was performed in Razi Hospital, Rasht, Iran, between March 2016 and August 2018 on a population of chronic obstructive pulmonary disease (COPD) patients (56 as COPD exacerbation group and 56 as COPD stable group). Study variables include age, sex, occupation, body mass index (BMI), cigarette consumption, duration of COPD, annual hospitalization, dyspnea, glycated hemoglobin (HbA1c), FEV1, and FEV1/FVC indices. Result The mean age of the participants was 63.92 ± 10.75 years. There was a significant difference in the hospitalization between the patients with both exacerbation and normal state of COPD (P ≤ 0.001). HbA1c in the patients with exacerbation of COPD was significantly higher than stable status (P = 0.001). Logistic regression showed that HbA1c levels and hospitalization were predictors of exacerbation of COPD. HbA1c levels were statistically significant in terms of hospitalization in patients with COPD exacerbation. There was a significant difference between the HbA1c levels and MMRC in patients with COPD. The percentage of HbA1c was associated with exacerbation of COPD and HbA1c is a good predictor of disease severity in patients with COPD. It also shows that patients with COPD exacerbation and severe COPD are at the higher risk of hyperglycemia.https://doi.org/10.1186/s13104-022-06217-7Glycated hemoglobin APulmonary DiseaseChronic obstructive |
| spellingShingle | Behrang Motamed Ali Alavi Foumani Azita Tangestaninezhad Mohammad Almasi Niloofar Faraji Alireza Jafarinezhad The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease BMC Research Notes Glycated hemoglobin A Pulmonary Disease Chronic obstructive |
| title | The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease |
| title_full | The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease |
| title_fullStr | The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease |
| title_short | The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease |
| title_sort | relationship between glycated hemoglobin a1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease |
| topic | Glycated hemoglobin A Pulmonary Disease Chronic obstructive |
| url | https://doi.org/10.1186/s13104-022-06217-7 |
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