Human Properdin Modulates Macrophage: Mycobacterium bovis BCG Interaction via Thrombospondin Repeats 4 and 5

Human Properdin Modulates Macrophage: Mycobacterium bovis BCG Interaction via Thrombospondin Repeats 4 and 5

Mycobacterium tuberculosis can proficiently enter macrophages and diminish complement activation on its cell surface. Within macrophages, the mycobacterium can suppress macrophage apoptosis and survive within the intracellular environment. Previously, we have shown that complement regulatory protein...

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Bibliographic Details
Main Authors: Maha Ahmed Al-Mozaini, Anthony G. Tsolaki, Munirah Abdul-Aziz, Suhair M. Abozaid, Mohammed N. Al-Ahdal, Ansar A. Pathan, Valarmathy Murugaiah, Evgeny M. Makarov, Anuvinder Kaur, Robert B. Sim, Uday Kishore, Lubna Kouser
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
complement
cytokine
properdin
macrophage
Mycobacterium tuberculosis
Mycobacterium bovis BCG
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00533/full

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