Myocardial defect detection using PET-CT: phantom studies.
It is expected that both noise and activity distribution can have impact on the detectability of a myocardial defect in a cardiac PET study. In this work, we performed phantom studies to investigate the detectability of a defect in the myocardium for different noise levels and activity distributions...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3914931?pdf=render |
| _version_ | 1828810721426669568 |
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| author | Eugene S Mananga Georges El Fakhri Joshua Schaefferkoetter Ali A Bonab Jinsong Ouyang |
| author_facet | Eugene S Mananga Georges El Fakhri Joshua Schaefferkoetter Ali A Bonab Jinsong Ouyang |
| author_sort | Eugene S Mananga |
| collection | DOAJ |
| description | It is expected that both noise and activity distribution can have impact on the detectability of a myocardial defect in a cardiac PET study. In this work, we performed phantom studies to investigate the detectability of a defect in the myocardium for different noise levels and activity distributions. We evaluated the performance of three reconstruction schemes: Filtered Back-Projection (FBP), Ordinary Poisson Ordered Subset Expectation Maximization (OP-OSEM), and Point Spread Function corrected OSEM (PSF-OSEM). We used the Channelized Hotelling Observer (CHO) for the task of myocardial defect detection. We found that the detectability of a myocardial defect is almost entirely dependent on the noise level and the contrast between the defect and its surroundings. |
| first_indexed | 2024-12-12T09:16:09Z |
| format | Article |
| id | doaj.art-36f85f223b3842379a4dbb5302da5031 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T09:16:09Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-36f85f223b3842379a4dbb5302da50312022-12-22T00:29:22ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0192e8820010.1371/journal.pone.0088200Myocardial defect detection using PET-CT: phantom studies.Eugene S ManangaGeorges El FakhriJoshua SchaefferkoetterAli A BonabJinsong OuyangIt is expected that both noise and activity distribution can have impact on the detectability of a myocardial defect in a cardiac PET study. In this work, we performed phantom studies to investigate the detectability of a defect in the myocardium for different noise levels and activity distributions. We evaluated the performance of three reconstruction schemes: Filtered Back-Projection (FBP), Ordinary Poisson Ordered Subset Expectation Maximization (OP-OSEM), and Point Spread Function corrected OSEM (PSF-OSEM). We used the Channelized Hotelling Observer (CHO) for the task of myocardial defect detection. We found that the detectability of a myocardial defect is almost entirely dependent on the noise level and the contrast between the defect and its surroundings.http://europepmc.org/articles/PMC3914931?pdf=render |
| spellingShingle | Eugene S Mananga Georges El Fakhri Joshua Schaefferkoetter Ali A Bonab Jinsong Ouyang Myocardial defect detection using PET-CT: phantom studies. PLoS ONE |
| title | Myocardial defect detection using PET-CT: phantom studies. |
| title_full | Myocardial defect detection using PET-CT: phantom studies. |
| title_fullStr | Myocardial defect detection using PET-CT: phantom studies. |
| title_full_unstemmed | Myocardial defect detection using PET-CT: phantom studies. |
| title_short | Myocardial defect detection using PET-CT: phantom studies. |
| title_sort | myocardial defect detection using pet ct phantom studies |
| url | http://europepmc.org/articles/PMC3914931?pdf=render |
| work_keys_str_mv | AT eugenesmananga myocardialdefectdetectionusingpetctphantomstudies AT georgeselfakhri myocardialdefectdetectionusingpetctphantomstudies AT joshuaschaefferkoetter myocardialdefectdetectionusingpetctphantomstudies AT aliabonab myocardialdefectdetectionusingpetctphantomstudies AT jinsongouyang myocardialdefectdetectionusingpetctphantomstudies |