Myocardial fibrosis induced by nonylphenol and its regulatory effect on the TGF-β1/LIMK1 signaling pathway

Myocardial fibrosis induced by nonylphenol and its regulatory effect on the TGF-β1/LIMK1 signaling pathway

Objective: We here explored whether perinatal nonylphenol (NP) exposure causes myocardial fibrosis (MF) during adulthood in offspring rats and determined the role of the TGF-β1/LIMK1 signaling pathway in NP-induced fibrosis in cardiac fibroblasts (CFs). Methods and results: Histopathology revealed i...

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Bibliographic Details
Main Authors: Mei Guo, Jie Xu, Xianping Long, Weichu Liu, Ahmad Zaharin Aris, Danli Yang, Ya Luo, Yuzhu Xu, Jie Yu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Nonylphenol
Cardiac fibroblasts
Myocardial fibrosis
TGF-β1/LIMK1 signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324001854

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http://www.sciencedirect.com/science/article/pii/S0147651324001854

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