Chimeric RHDV Virus-Like Particles Displaying Foot-and-Mouth Disease Virus Epitopes Elicit Neutralizing Antibodies and Confer Partial Protection in Pigs

Chimeric RHDV Virus-Like Particles Displaying Foot-and-Mouth Disease Virus Epitopes Elicit Neutralizing Antibodies and Confer Partial Protection in Pigs

Currently there is a clear trend towards the establishment of virus-like particles (VLPs) as a powerful tool for vaccine development. VLPs are tunable nanoparticles that can be engineered to be used as platforms for multimeric display of foreign antigens. We have previously reported that VLPs derive...

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Bibliographic Details
Main Authors: Giselle Rangel, Juan Bárcena, Noelia Moreno, Carlos P. Mata, José R. Castón, Alí Alejo, Esther Blanco
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Vaccines
Subjects:
virus-like particles (VLPs)
chimeric VLPs
nanoparticles
vaccine platform
RHDV
FMDV
Online Access:https://www.mdpi.com/2076-393X/9/5/470

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