Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication
Abstract Herein, a multifunctional bilayer wound patch is developed by integrating a debonding‐on‐demand polymeric tissue adhesive (DDPTA) with an ionic conducting elastomer (ICE). As a skin adhesive layer, the DDPTA is soft and adherent at skin temperature but hard and non‐tacky when cooled, so it...
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| Format: | Article |
| Language: | English |
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Wiley
2022-10-01
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| Series: | Advanced Science |
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| Online Access: | https://doi.org/10.1002/advs.202202635 |
| _version_ | 1811241311322243072 |
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| author | Qiankun Zeng Fangbing Wang Ruixuan Hu Xuyin Ding Yifan Lu Guoyue Shi Hossam Haick Min Zhang |
| author_facet | Qiankun Zeng Fangbing Wang Ruixuan Hu Xuyin Ding Yifan Lu Guoyue Shi Hossam Haick Min Zhang |
| author_sort | Qiankun Zeng |
| collection | DOAJ |
| description | Abstract Herein, a multifunctional bilayer wound patch is developed by integrating a debonding‐on‐demand polymeric tissue adhesive (DDPTA) with an ionic conducting elastomer (ICE). As a skin adhesive layer, the DDPTA is soft and adherent at skin temperature but hard and non‐tacky when cooled, so it provides unique temperature‐triggered quick adhesion and non‐forced detachment from the skin. During use, the dense surface of the DDPTA prevents blood infiltration and reduces unnecessary blood loss with gentle pressing. Moreover, its hydrophobic matrix helps to repel blood and prevents the formation of clots, thus precluding wound tearing during its removal. This unique feature enables the DDPTA to avoid the severe deficiencies of hydrophilic adhesives, providing a reliable solution for a wide range of secondary wound injuries. The DDPTA is versatile in that it can be covered with ICE to configure a DDPTA@ICE patch for initiating non‐verbal communication systems by the fingers, leading toward sign language recognition and a remote clinical alarm system. This multifunctional wound patch with debonding‐on‐demand can promote a new style of tissue sealant for convenient clinical communication. |
| first_indexed | 2024-04-12T13:34:29Z |
| format | Article |
| id | doaj.art-36fc6392926b478f8289a88750321fab |
| institution | Directory Open Access Journal |
| issn | 2198-3844 |
| language | English |
| last_indexed | 2024-04-12T13:34:29Z |
| publishDate | 2022-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj.art-36fc6392926b478f8289a88750321fab2022-12-22T03:31:04ZengWileyAdvanced Science2198-38442022-10-01929n/an/a10.1002/advs.202202635Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical CommunicationQiankun Zeng0Fangbing Wang1Ruixuan Hu2Xuyin Ding3Yifan Lu4Guoyue Shi5Hossam Haick6Min Zhang7School of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaSchool of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaSchool of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaSchool of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaSchool of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaSchool of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaDepartment of Chemical Engineering and Russell Berrie Nanotechnology Institute Technion – Israel Institute of Technology Haifa 320003 IsraelSchool of Chemistry and Molecular Engineering Shanghai Key Laboratory for Urban Ecological Processes and Eco‐Restoration Shanghai Key Laboratory of Multidimensional Information Processing Engineering Research Centre for Nanophotonics and Advanced Instrument (Ministry of Education) East China Normal University Shanghai 200241 ChinaAbstract Herein, a multifunctional bilayer wound patch is developed by integrating a debonding‐on‐demand polymeric tissue adhesive (DDPTA) with an ionic conducting elastomer (ICE). As a skin adhesive layer, the DDPTA is soft and adherent at skin temperature but hard and non‐tacky when cooled, so it provides unique temperature‐triggered quick adhesion and non‐forced detachment from the skin. During use, the dense surface of the DDPTA prevents blood infiltration and reduces unnecessary blood loss with gentle pressing. Moreover, its hydrophobic matrix helps to repel blood and prevents the formation of clots, thus precluding wound tearing during its removal. This unique feature enables the DDPTA to avoid the severe deficiencies of hydrophilic adhesives, providing a reliable solution for a wide range of secondary wound injuries. The DDPTA is versatile in that it can be covered with ICE to configure a DDPTA@ICE patch for initiating non‐verbal communication systems by the fingers, leading toward sign language recognition and a remote clinical alarm system. This multifunctional wound patch with debonding‐on‐demand can promote a new style of tissue sealant for convenient clinical communication.https://doi.org/10.1002/advs.202202635clinical communicationionic conducting elastomerpolymeric adhesivewound patches |
| spellingShingle | Qiankun Zeng Fangbing Wang Ruixuan Hu Xuyin Ding Yifan Lu Guoyue Shi Hossam Haick Min Zhang Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication Advanced Science clinical communication ionic conducting elastomer polymeric adhesive wound patches |
| title | Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication |
| title_full | Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication |
| title_fullStr | Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication |
| title_full_unstemmed | Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication |
| title_short | Debonding‐On‐Demand Polymeric Wound Patches for Minimal Adhesion and Clinical Communication |
| title_sort | debonding on demand polymeric wound patches for minimal adhesion and clinical communication |
| topic | clinical communication ionic conducting elastomer polymeric adhesive wound patches |
| url | https://doi.org/10.1002/advs.202202635 |
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