Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters
Minor genera actinomycetes are considered a promising source of new secondary metabolites. The strain <i>Kribbella</i> sp. CA-293567 produces sandramycin and kribbellichelins A & B In this work, we describe the complete genome sequencing of this strain and the in silico identificatio...
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| Format: | Article |
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MDPI AG
2023-01-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/2/265 |
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| author | Marina Sánchez-Hidalgo María Jesús García Ignacio González Daniel Oves-Costales Olga Genilloud |
| author_facet | Marina Sánchez-Hidalgo María Jesús García Ignacio González Daniel Oves-Costales Olga Genilloud |
| author_sort | Marina Sánchez-Hidalgo |
| collection | DOAJ |
| description | Minor genera actinomycetes are considered a promising source of new secondary metabolites. The strain <i>Kribbella</i> sp. CA-293567 produces sandramycin and kribbellichelins A & B In this work, we describe the complete genome sequencing of this strain and the in silico identification of biosynthetic gene clusters (BGCs), focusing on the pathways encoding sandramycin and kribbellichelins A–B. We also present a comparative analysis of the biosynthetic potential of 38 publicly available genomes from <i>Kribbella</i> strains. |
| first_indexed | 2024-03-11T08:23:57Z |
| format | Article |
| id | doaj.art-36fe16dc836044f9b2ad51d61326085c |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-11T08:23:57Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-36fe16dc836044f9b2ad51d61326085c2023-11-16T22:13:30ZengMDPI AGMicroorganisms2076-26072023-01-0111226510.3390/microorganisms11020265Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene ClustersMarina Sánchez-Hidalgo0María Jesús García1Ignacio González2Daniel Oves-Costales3Olga Genilloud4Fundación MEDINA, Avenida del Conocimiento 34, PTS Health Sciences Technology Park, 18016 Granada, SpainFundación MEDINA, Avenida del Conocimiento 34, PTS Health Sciences Technology Park, 18016 Granada, SpainFundación MEDINA, Avenida del Conocimiento 34, PTS Health Sciences Technology Park, 18016 Granada, SpainFundación MEDINA, Avenida del Conocimiento 34, PTS Health Sciences Technology Park, 18016 Granada, SpainFundación MEDINA, Avenida del Conocimiento 34, PTS Health Sciences Technology Park, 18016 Granada, SpainMinor genera actinomycetes are considered a promising source of new secondary metabolites. The strain <i>Kribbella</i> sp. CA-293567 produces sandramycin and kribbellichelins A & B In this work, we describe the complete genome sequencing of this strain and the in silico identification of biosynthetic gene clusters (BGCs), focusing on the pathways encoding sandramycin and kribbellichelins A–B. We also present a comparative analysis of the biosynthetic potential of 38 publicly available genomes from <i>Kribbella</i> strains.https://www.mdpi.com/2076-2607/11/2/265<i>Kribbella</i>sandramycinkribbellichelingenome miningbiosynthetic gene clusterminor genera of actinomycetes |
| spellingShingle | Marina Sánchez-Hidalgo María Jesús García Ignacio González Daniel Oves-Costales Olga Genilloud Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters Microorganisms <i>Kribbella</i> sandramycin kribbellichelin genome mining biosynthetic gene cluster minor genera of actinomycetes |
| title | Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters |
| title_full | Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters |
| title_fullStr | Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters |
| title_full_unstemmed | Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters |
| title_short | Complete Genome Sequence Analysis of <i>Kribbella</i> sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters |
| title_sort | complete genome sequence analysis of i kribbella i sp ca 293567 and identification of the kribbellichelins a b and sandramycin biosynthetic gene clusters |
| topic | <i>Kribbella</i> sandramycin kribbellichelin genome mining biosynthetic gene cluster minor genera of actinomycetes |
| url | https://www.mdpi.com/2076-2607/11/2/265 |
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