Metabolic protection by the dietary flavonoid 7,8-dihydroxyflavone requires an intact gut microbiome

Metabolic protection by the dietary flavonoid 7,8-dihydroxyflavone requires an intact gut microbiome

Background7,8-dihydroxyflavone (DHF) is a naturally occurring flavonoid found in Godmania, Tridax, and Primula species that confers protection against high-fat diet (HFD) induced metabolic pathologies selectively in female mice. We have previously reported that this metabolic protection is associate...

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Bibliographic Details
Main Authors: Priyanka Sharma, Camila Silva, Sarah Pfreundschuh, Hong Ye, Harini Sampath
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Nutrition
Subjects:
DHF
microbiome
TrkB
brown adipose tissue
sex effects
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.987956/full

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