Adaptive mutations and replacements of virulence traits in the Escherichia coli O104:H4 outbreak population.

Adaptive mutations and replacements of virulence traits in the Escherichia coli O104:H4 outbreak population.

The sequencing of highly virulent Escherichia coli O104:H4 strains isolated during the outbreak of bloody diarrhea and hemolytic uremic syndrome in Europe in 2011 revealed a genome that contained a Shiga toxin encoding prophage and a plasmid encoding enteroaggregative fimbriae. Here, we present the...

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Bibliographic Details
Main Authors: Lionel Guy, Cecilia Jernberg, Jenny Arvén Norling, Sofie Ivarsson, Ingela Hedenström, Öjar Melefors, Ulrika Liljedahl, Lars Engstrand, Siv G E Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3651199?pdf=render

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