Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents

Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents

Abstract Background Current therapeutic agents, including nifurtimox and benznidazole, are not sufficiently effective in the chronic phase of Trypanosoma cruzi infection and are accompanied by various side effects. In this study, 120 kinds of extracts from medicinal herbs used for Kampo formulations...

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Bibliographic Details
Main Authors:	Yuki Tayama, Shusaku Mizukami, Kazufumi Toume, Katsuko Komatsu, Tetsuo Yanagi, Takeshi Nara, Paul Tieu, Nguyen Tien Huy, Shinjiro Hamano, Kenji Hirayama
Format:	Article
Language:	English
Published:	BMC 2023-03-01
Series:	Tropical Medicine and Health
Subjects:	Trypanosoma cruzi Chagas disease Coptis rhizome extract Coptisine chloride Isoquinoline alkaloid
Online Access:	https://doi.org/10.1186/s41182-023-00502-2

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