Breast Cancer in Mosul: A Survival Analysis
Breast cancer is the most common cancer in women, and the major cause of death. This study was conducted in order to make a descriptive study and survival analysis for breast cancer patients in Mosul. Two hundred forty-six early diagnosed women with breast cancer out of 290 patients were included d...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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College of Pharmacy / Mustansiriyah University
2020-06-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/695 |
| _version_ | 1797223847504642048 |
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| author | Taha HT Al-Saigh Shahbaa A Al-bayati Shatha A Abdul-mawjood Faris A Ahmed |
| author_facet | Taha HT Al-Saigh Shahbaa A Al-bayati Shatha A Abdul-mawjood Faris A Ahmed |
| author_sort | Taha HT Al-Saigh |
| collection | DOAJ |
| description |
Breast cancer is the most common cancer in women, and the major cause of death. This study was conducted in order to make a descriptive study and survival analysis for breast cancer patients in Mosul. Two hundred forty-six early diagnosed women with breast cancer out of 290 patients were included during the period from March 2007 to February 2012. The average follows up was 36.
months (range: 11-67 months). The patients were undergone modified radical removal of the breast, chemotherapy and deep radiation. Patients with estrogen positive were given tamoxifen for five years. Patients with Her2/neu positive were given trastuzumab with docytaxil for one year. Only 25 patients (10.2%) died during the study. The highest incidence of breast cancer (35.8%) was between the ages 51 ≥ 60 years. The presentation of cancer was high (90.1%) in the lumber. Tumor in the right side (66.35%) was significantly higher than the left side. Metastasis was high (25%) and most of them in the liver (19.1%). The percentage of patients with positive estrogen, progesterone, and Her2/neu receptors were not different from negative receptors. Cox regression analysis showed that metastasis had significant effect on death (hazard ratio=2.917). Age 31 ≥ 40 years was the least affected age (hazard ratio=0.034). In conclusion, survival rate of breast cancer patients in Mosul is high due to good management. The early detection of cancer is the best way for survival of the patients, by developing the educational programs.
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| first_indexed | 2024-04-24T13:43:44Z |
| format | Article |
| id | doaj.art-370c9e39886f4bfc8fcd5f7fe4dae306 |
| institution | Directory Open Access Journal |
| issn | 1815-0993 2959-183X |
| language | English |
| last_indexed | 2024-04-24T13:43:44Z |
| publishDate | 2020-06-01 |
| publisher | College of Pharmacy / Mustansiriyah University |
| record_format | Article |
| series | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| spelling | doaj.art-370c9e39886f4bfc8fcd5f7fe4dae3062024-04-04T07:00:45ZengCollege of Pharmacy / Mustansiriyah UniversityAl-Mustansiriyah Journal of Pharmaceutical Sciences1815-09932959-183X2020-06-0120210.32947/ajps.v20i2.695Breast Cancer in Mosul: A Survival AnalysisTaha HT Al-Saigh0Shahbaa A Al-bayati1Shatha A Abdul-mawjood2Faris A Ahmed3* Ninevaha College of Medicine, University of Ninevah, Mosul* Ninevaha College of Medicine, University of Ninevah, Mosul* Ninevaha College of Medicine, University of Ninevah, MosulCollege of Pharmacy, University of Uruk, Baghdad, Iraq Breast cancer is the most common cancer in women, and the major cause of death. This study was conducted in order to make a descriptive study and survival analysis for breast cancer patients in Mosul. Two hundred forty-six early diagnosed women with breast cancer out of 290 patients were included during the period from March 2007 to February 2012. The average follows up was 36. months (range: 11-67 months). The patients were undergone modified radical removal of the breast, chemotherapy and deep radiation. Patients with estrogen positive were given tamoxifen for five years. Patients with Her2/neu positive were given trastuzumab with docytaxil for one year. Only 25 patients (10.2%) died during the study. The highest incidence of breast cancer (35.8%) was between the ages 51 ≥ 60 years. The presentation of cancer was high (90.1%) in the lumber. Tumor in the right side (66.35%) was significantly higher than the left side. Metastasis was high (25%) and most of them in the liver (19.1%). The percentage of patients with positive estrogen, progesterone, and Her2/neu receptors were not different from negative receptors. Cox regression analysis showed that metastasis had significant effect on death (hazard ratio=2.917). Age 31 ≥ 40 years was the least affected age (hazard ratio=0.034). In conclusion, survival rate of breast cancer patients in Mosul is high due to good management. The early detection of cancer is the best way for survival of the patients, by developing the educational programs. https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/695Breast cancer, survival analysis, Her2/neu, hazard ratio. |
| spellingShingle | Taha HT Al-Saigh Shahbaa A Al-bayati Shatha A Abdul-mawjood Faris A Ahmed Breast Cancer in Mosul: A Survival Analysis Al-Mustansiriyah Journal of Pharmaceutical Sciences Breast cancer, survival analysis, Her2/neu, hazard ratio. |
| title | Breast Cancer in Mosul: A Survival Analysis |
| title_full | Breast Cancer in Mosul: A Survival Analysis |
| title_fullStr | Breast Cancer in Mosul: A Survival Analysis |
| title_full_unstemmed | Breast Cancer in Mosul: A Survival Analysis |
| title_short | Breast Cancer in Mosul: A Survival Analysis |
| title_sort | breast cancer in mosul a survival analysis |
| topic | Breast cancer, survival analysis, Her2/neu, hazard ratio. |
| url | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/695 |
| work_keys_str_mv | AT tahahtalsaigh breastcancerinmosulasurvivalanalysis AT shahbaaaalbayati breastcancerinmosulasurvivalanalysis AT shathaaabdulmawjood breastcancerinmosulasurvivalanalysis AT farisaahmed breastcancerinmosulasurvivalanalysis |