CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION

Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating l...

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Bibliographic Details
Main Authors: V.P. Buzulina, I.A. Pronchenko, I.P. Yermakova, M.N. Kornilov, E.B. Yaroshenko, D.S. Mnatsakanyan, T.K. Koliashvili, N.P. Shmerko
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2012-03-01
Series:Вестник трансплантологии и искусственных органов
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Online Access:https://journal.transpl.ru/vtio/article/view/108
Description
Summary:Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating levels OC and P1NP with normal levels BALP in recipients without clinical postoperative complication; combination lower levels OC and BALP with normal levels P1NP in recipients as a result of corticosteroid therapy prior/ following transplantation; superior levels P1NP with normal levels OC and BALP which results excessive accumulation hepatic collagen formation in recipients with postoperative clinical complication.
ISSN:1995-1191